ENSMUSG00000051397


Mus musculus

Features
Gene ID: ENSMUSG00000051397
  
Biological name :Tacstd2
  
Synonyms : Q8BGV3 / Tacstd2 / Tumor-associated calcium signal transducer 2
  
Possible biological names infered from orthology : P09758
  
Species: Mus musculus
  
Chr. number: 6
Strand: -1
Band: C1
Gene start: 67534062
Gene end: 67535796
  
Corresponding Affymetrix probe sets: 10545168 (MoGene1.0st)   1423323_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000060099
NCBI entrez gene - 56753     See in Manteia.
MGI - MGI:1861606
RefSeq - NM_020047
RefSeq Peptide - NP_064431
swissprot - Q8BGV3
Ensembl - ENSMUSG00000051397
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 epcamENSDARG00000040534Danio rerio
 TACSTD2ENSGALG00000010867Gallus gallus
 P09758ENSG00000184292Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Epcam / Q99JW5 / Epithelial cell adhesion molecule / P16422*ENSMUSG0000004539452


Protein motifs (from Interpro)
Interpro ID Name
 IPR000716  Thyroglobulin type-1
 IPR036857  Thyroglobulin type-1 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010633 negative regulation of epithelial cell migration IDA
 biological_processGO:0050678 regulation of epithelial cell proliferation IEP
 biological_processGO:0051497 negative regulation of stress fiber assembly IDA
 biological_processGO:0060675 ureteric bud morphogenesis IEP
 biological_processGO:0090191 negative regulation of branching involved in ureteric bud morphogenesis IDA
 biological_processGO:0098609 cell-cell adhesion IBA
 biological_processGO:1900025 negative regulation of substrate adhesion-dependent cell spreading IDA
 biological_processGO:1900028 negative regulation of ruffle assembly IDA
 biological_processGO:2000146 negative regulation of cell motility IDA
 biological_processGO:2000738 positive regulation of stem cell differentiation IDA
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0009925 basal plasma membrane IDA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016328 lateral plasma membrane IDA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002038 carcinoma "malignant neoplasm arising from epithelial cells, usually glandular or squamous" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:58877]
Show

Allelic Composition: Cdkn2atm1Cjs/Cdkn2atm1Cjs,Tacstd2tm1Lsm/Tacstd2tm1Lsm
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0002724 enhanced wound healing "increased ability to self-repair and close wounds" [dlb:Donna Burkart , Mouse Genome Informatics Curator, J:42016]
Show

Allelic Composition: Cdkn2atm1Cjs/Cdkn2atm1Cjs,Tacstd2tm1Lsm/Tacstd2tm1Lsm
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0003941 abnormal skin development "anomaly in the formation of of the membranous protective covering of the body" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cdkn2atm1Cjs/Cdkn2atm1Cjs,Tacstd2tm1Lsm/Tacstd2tm1Lsm
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0009583 increased keratinocyte proliferation "increase in the expansion rate of keratinocytes by cell division" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cdkn2atm1Cjs/Cdkn2atm1Cjs,Tacstd2tm1Lsm/Tacstd2tm1Lsm
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0009704 skin squamous cell carcinoma "a skin carcinoma derived from stratified squamous epithelium" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cdkn2atm1Cjs/Cdkn2atm1Cjs,Tacstd2tm1Lsm/Tacstd2tm1Lsm
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0010367 increased spindle cell carcinoma incidence "greater than the expected number of a highly malignant variant of squamous cell carcinoma, occurring in a specific population in a given time period; spindle cell carcinoma shows biphasic proliferation of conventional SCC component and malignant spindle shape cells with sarcomatous appearance" [PMID:19040765]
Show

Allelic Composition: Cdkn2atm1Cjs/Cdkn2atm1Cjs,Tacstd2tm1Lsm/Tacstd2tm1Lsm
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0012193 increased keratinocyte migration "increased or faster movement of keratinocyes or their precursors to the appropriate location in the body" [MGI:csmith]
Show

Allelic Composition: Cdkn2atm1Cjs/Cdkn2atm1Cjs,Tacstd2tm1Lsm/Tacstd2tm1Lsm
Genetic Background: involves: 129X1/SvJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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