| MP:0000465 | gastrointestinal hemorrhage | "bleeding in the stomach and/or the intestines" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, tc:Teresa Chu , Mouse Genome Informatics Curator, J:60896] |
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Allelic Composition: Fras1tm1.2Pjsc/Fras1tm1.2Pjsc
Genetic Background: involves: C57BL/6 * FVB/N * SJL
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| MP:0000477 | abnormal intestine morphology | "malformation of the digestive tube passing from the stomach to the anus" [J:48968] |
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Allelic Composition: Ntrk2tm2.1Tes/Ntrk2tm2.1Tes
Genetic Background: involves: 129S4/SvJae * C57BL/6J
Allelic Composition: Epcamtm1.2Msiv/Epcamtm1.2Msiv
Genetic Background: involves: C57BL/6 * FVB/N * SJL
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| MP:0000479 | abnormal intestinal cell | "anomalous structure or development of the cells comprising the intestine" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: EpcamGt(RST412)Byg/EpcamGt(RST412)Byg
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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| MP:0000488 | abnormal intestinal epithelium morphology | "anomalous structure or development of the cellular avascular layer of the digestive tube passing from the stomach to the anus" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: EpcamGt(RST412)Byg/EpcamGt(RST412)Byg
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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| MP:0000490 | abnormal crypts of Lieberkuhn morphology | "malformation or defects in the tubular intestinal glands found in the mucosal membranes" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Ntrk2tm2.1Tes/Ntrk2tm2.1Tes
Genetic Background: involves: 129S4/SvJae * C57BL/6J
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| MP:0000495 | abnormal colon morphology | "malformation of the portion of the large intestine between the cecum and the rectum" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: EpcamGt(RST412)Byg/EpcamGt(RST412)Byg
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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| MP:0000511 | abnormal intestinal mucosa morphology | "structural or developmental anomalies of the mucous lining of the intestine; this consists of epithelium, lamina, propria, and a layer of smooth muscle cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Fras1tm1.2Pjsc/Fras1tm1.2Pjsc
Genetic Background: involves: C57BL/6 * FVB/N * SJL
Allelic Composition: EpcamGt(RST412)Byg/EpcamGt(RST412)Byg
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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| MP:0001265 | reduced body size | "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170] |
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Allelic Composition: Myo7am1Btlr/Myo7am1Btlr
Genetic Background: C57BL/6J-Myo7am1Btlr
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| MP:0001634 | internal hemorrhage | "blood loss in the interior of the body due to vessel rupture or dysmorphology " [J:23170] |
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Allelic Composition: EpcamGt(RST412)Byg/EpcamGt(RST412)Byg
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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| MP:0001698 | reduced embryo size | "smaller proportions of embryo compared to littermates" [J:61790] |
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Allelic Composition: Aw/Aw,As/As
Genetic Background: involves: 101/H * C3H/HeH
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| MP:0001713 | reduced trophoblast cell number | "fewer than normal number of cells of the extraembryonic cell layer that contributes to the placenta" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:23171] |
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Allelic Composition: Aw/Aw,As/As
Genetic Background: involves: 101/H * C3H/HeH
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| MP:0001716 | abnormal placental labyrinth | "malformed structure where embryonic blood vessels are surrounded by trophoblast cells and maternal blood" [J:23171] |
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Allelic Composition: Aw/Aw,As/As
Genetic Background: involves: 101/H * C3H/HeH
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| MP:0001730 | embryonic growth arrest | "the cessation of development beyond a particular stage" [J:17509] |
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Allelic Composition: Aw/Aw,As/As
Genetic Background: involves: 101/H * C3H/HeH
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| MP:0001732 | postnatal growth retardation | "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Fras1tm1.2Pjsc/Fras1tm1.2Pjsc
Genetic Background: involves: C57BL/6 * FVB/N * SJL
Allelic Composition: EpcamGt(RST412)Byg/EpcamGt(RST412)Byg
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Epcamtm1.2Msiv/Epcamtm1.2Msiv
Genetic Background: involves: C57BL/6 * FVB/N * SJL
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| MP:0002581 | abnormal ileum morphology | "malformation of the portion of the small intestine that extends from the jejunum to the colon" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:70183] |
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Allelic Composition: Epcamtm1.2Msiv/Epcamtm1.2Msiv
Genetic Background: involves: C57BL/6 * FVB/N * SJL
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| MP:0002621 | delayed neural tube closure | "delayed fusion of the neuroepithelial layer in early development" [J:79790, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator] |
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Allelic Composition: Aw/Aw,As/As
Genetic Background: involves: 101/H * C3H/HeH
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| MP:0003091 | abnormal cell migration | "defect in the movement of cells during developmental processes" [smb:Susan M. Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Dnah11b2b1203Clo/Dnah11b2b1203Clo
Genetic Background: C57BL/6J-Dnah11b2b1203Clo
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| MP:0003271 | abnormal duodenum morphology | "malformation in the first division of the small intestine that extends from the pyloris to the junction with the jejunum " [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Epcamtm1.2Msiv/Epcamtm1.2Msiv
Genetic Background: involves: C57BL/6 * FVB/N * SJL
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| MP:0003288 | intestinal edema | "an accumulation of an excessive amount of serous fluid in the intestine or intestinal cells " [ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Epcamtm1.2Msiv/Epcamtm1.2Msiv
Genetic Background: involves: C57BL/6 * FVB/N * SJL
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| MP:0003306 | small intestinal inflammation | "local accumulation of fluid, plasma proteins, and leukocytes in the small intestine" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Epcamtm1.2Msiv/Epcamtm1.2Msiv
Genetic Background: involves: C57BL/6 * FVB/N * SJL
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| MP:0003720 | abnormal neural tube closure | "abnormal invagination and fusion of the neuroepithelial layer in early development" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator, J:99099] |
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Allelic Composition: Aw/Aw,As/As
Genetic Background: involves: 101/H * C3H/HeH
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| MP:0004002 | abnormal jejunum morphology | "malformation of the portion of the small intestine that extends from the duodenum to the ileum" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Epcamtm1.2Msiv/Epcamtm1.2Msiv
Genetic Background: involves: C57BL/6 * FVB/N * SJL
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| MP:0004259 | small placenta | "reduced size of the size or shape of the organ of metabolic interchange between fetus and mother" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Aw/Aw,As/As
Genetic Background: involves: 101/H * C3H/HeH
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| MP:0005036 | diarrhea | "abnormally frequent discharge of semi-solid or fluid fecal matter from the bowel" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Fras1tm1.2Pjsc/Fras1tm1.2Pjsc
Genetic Background: involves: C57BL/6 * FVB/N * SJL
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| MP:0005048 | thrombosis | "formation within a tissue or the vascular lumen of a thrombus, an aggregation of coagulated blood containing platelets, fibrin, and entrapped cellular elements " [Pathology:ISBN 0-397-51047-0, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Aw/Aw,As/As
Genetic Background: involves: 101/H * C3H/HeH
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| MP:0005202 | lethargy | "mild impairment of consciousness resulting in reduced alertness and awareness; ultimately due to generalized brain dysfunction" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Epcamtm1.2Msiv/Epcamtm1.2Msiv
Genetic Background: involves: C57BL/6 * FVB/N * SJL
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| MP:0005362 | abnormal Langerhans cell physiology | "atypical or failure of normal function of the phagocytic dendritic cells principally found in the epidemis" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Dnah11b2b1203Clo/Dnah11b2b1203Clo
Genetic Background: C57BL/6J-Dnah11b2b1203Clo
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| MP:0005617 | increased susceptibility to type IV hypersensitivity reaction | "greater likelihood of developing an antigen-elicited cellular immune reaction that results in tissue damage, but does not require Ab participation; the response is seen at the area of contact " [Pathology:ISBN 0-397-51047-0, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Dnah11b2b1203Clo/Dnah11b2b1203Clo
Genetic Background: C57BL/6J-Dnah11b2b1203Clo
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| MP:0008117 | abnormal Langerhans cell morphology | "any structural anomaly of a stellate dendritic cell of myeloid origin, that appears clear on light microscopy and has a dark-staining, indented nucleus and characteristic inclusions (Birbeck granules) in the cytoplasm; Langerhans cells are found principally in the stratum spinosum of the epidermis, but they also occur in other stratified epithelia and have been identified in the lung, lymph nodes, spleen, and thymus" [CL:0000453, ISBN:0781735149, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Dnah11b2b1203Clo/Dnah11b2b1203Clo
Genetic Background: C57BL/6J-Dnah11b2b1203Clo
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| MP:0008489 | postnatal slow weight gain | "the weight gain over a span of postnatal developmental time is slower than controls, with or without ever attaining a similar weight to controls as adults" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: EpcamGt(RST412)Byg/EpcamGt(RST412)Byg
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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| MP:0008882 | abnormal enterocyte physiology | "any functional anomaly of the epithelial cells that have an apical plasma membrane folded into microvilli to provide ample surface for the absorption of nutrients from the intestinal lumen" [CL:0000584, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Epcamtm1.2Msiv/Epcamtm1.2Msiv
Genetic Background: involves: C57BL/6 * FVB/N * SJL
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| MP:0008883 | abnormal enterocyte proliferation | "anomaly in the ability of the enterocyte cell population to undergo expansion by cell division" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Epcamtm1.2Msiv/Epcamtm1.2Msiv
Genetic Background: involves: C57BL/6 * FVB/N * SJL
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| MP:0010155 | abnormal intestine physiology | "any functional anomaly of the digestive tube passing from the stomach to the anus" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Fras1tm1.2Pjsc/Fras1tm1.2Pjsc
Genetic Background: involves: C57BL/6 * FVB/N * SJL
Allelic Composition: EpcamGt(RST412)Byg/EpcamGt(RST412)Byg
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Epcamtm1.2Msiv/Epcamtm1.2Msiv
Genetic Background: involves: C57BL/6 * FVB/N * SJL
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| MP:0011085 | complete postnatal lethality | "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
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Allelic Composition: EpcamGt(RST412)Byg/EpcamGt(RST412)Byg
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Epcamtm1.2Msiv/Epcamtm1.2Msiv
Genetic Background: involves: C57BL/6 * FVB/N * SJL
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| MP:0011098 | complete embryonic lethality during organogenesis | "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith] |
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Allelic Composition: Aw/Aw,As/As
Genetic Background: involves: 101/H * C3H/HeH
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| MP:0011112 | partial lethality during fetal growth through weaning | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between the completion of organogenesis and weaning age (Mus: E14 to approximately 3 weeks of age)" [MGI:csmith] |
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Allelic Composition: Fras1tm1.2Pjsc/Fras1tm1.2Pjsc
Genetic Background: involves: C57BL/6 * FVB/N * SJL
Allelic Composition: Epcamtm1.2Hmd/Epcamtm1.2Hmd
Genetic Background: involves: 129 * C57BL/6
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| MP:0014083 | blunted small intestinal villi | "abnormal flattening of the surface of the tiny hair-like projections which protrude from the inside of the small intestine and contain blood vessels that capture digested nutrients that are absorbed through the intestinal wall; usually due to intestinal damage or injury" [MGI:Anna, PMID:16679353] |
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Allelic Composition: Epcamtm1.2Msiv/Epcamtm1.2Msiv
Genetic Background: involves: C57BL/6 * FVB/N * SJL
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