ENSMUSG00000051879


Mus musculus

Features
Gene ID: ENSMUSG00000051879
  
Biological name :Krt71
  
Synonyms : Keratin, type II cytoskeletal 71 / Krt71 / Q9R0H5
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 15
Strand: -1
Band: F2
Gene start: 101733949
Gene end: 101743109
  
Corresponding Affymetrix probe sets: 10432799 (MoGene1.0st)   1448457_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000023710
NCBI entrez gene - 56735     See in Manteia.
MGI - MGI:1861586
RefSeq - NM_019956
RefSeq Peptide - NP_064340
swissprot - Q9R0H5
Ensembl - ENSMUSG00000051879
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Krt73 / Q6NXH9 / Keratin, type II cytoskeletal 73 / Q86Y46* / keratin 73*ENSMUSG0000006366177
Krt72 / Q6IME9 / Keratin, type II cytoskeletal 72 / Q14CN4* / keratin 72*ENSMUSG0000005660571
Krt2 / Q3TTY5 / Keratin, type II cytoskeletal 2 epidermal / P35908* / keratin 2*ENSMUSG0000006420155
Krt1 / P04104 / Keratin, type II cytoskeletal 1 ENSMUSG0000004683455
Krt77 / Q6IFZ6 / keratin 77 / Q7Z794*ENSMUSG0000006759454
Krt84 / Q99M73 / Keratin, type II cuticular Hb4 / Q9NSB2* / keratin 84*ENSMUSG0000004429448
Krt78 / keratin 78 / Q8N1N4*ENSMUSG0000005046343
Krt82 / Q99M74 / Keratin, type II cuticular Hb2 / Q9NSB4* / keratin 82*ENSMUSG0000004954843
Krt87 / Q6IMF0 / Keratin, type II cuticular 87 / KRT81* / KRT83* / KRT86* / O43790* / Q14533* / P78385* / keratin 81* / keratin 83* / keratin 86*ENSMUSG0000004764142
Krt81 / Q9ERE2 / Keratin, type II cuticular Hb1 / KRT83* / KRT86* / P78385* / Q14533* / O43790* / keratin 81* / keratin 83* / keratin 86*ENSMUSG0000006761541
Krt86 / P97861 / keratin 86 / KRT83* / KRT81* / O43790* / P78385* / Q14533* / keratin 83* / keratin 81*ENSMUSG0000006761441
Krt83 / KRT81* / KRT86* / Q14533* / O43790* / P78385* / keratin 83* / keratin 81* / keratin 86*ENSMUSG0000006761341
Krt80 / Q0VBK2 / Keratin, type II cytoskeletal 80 / Q6KB66* / keratin 80*ENSMUSG0000003718532


Protein motifs (from Interpro)
Interpro ID Name
 IPR001664  Intermediate filament protein
 IPR003054  Keratin, type II
 IPR018039  Intermediate filament protein, conserved site
 IPR032444  Keratin type II head


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0031069 hair follicle morphogenesis ISS
 biological_processGO:0045109 intermediate filament organization ISS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005882 intermediate filament IEA
 cellular_componentGO:0045095 keratin filament ISO
 molecular_functionGO:0005198 structural molecule activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000377 abnormal hair follicle "malformed invagination of the epidermis from which the hair shaft develops" [J:65031]
Show

Allelic Composition: Bmp4tm1Blh/Bmp4tm3.1Blh,Tg(Tnnt2-cre)5Blh/0
Genetic Background: involves: 129S/Sv * Black Swiss * C57BL/6 * DBA/2 * ICR

Allelic Composition: Krt71Cal4/?
Genetic Background: C57BL/6J-Krt71Cal4/GrsrJ

Allelic Composition: Krt71Ca-Rin/?
Genetic Background: C57BL/6Slc-Krt71Ca-Rin

 MP:0000410 waved hair "hair or fur having undulations or a sinusoidal shape" [J:47620]
Show

Allelic Composition: Ccr8tm1Gma/Ccr8tm1Gma
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

Allelic Composition: Krt71Rgsc689/?
Genetic Background: involves: C57BL/6J * DBA/2J

Allelic Composition: Krt71Cal4/?
Genetic Background: C57BL/6J-Krt71Cal4/GrsrJ

Allelic Composition: Krt71Mhdarco12/Krt71Mhdarco12
Genetic Background: C3HeB/FeJ-Krt71Mhdarco12

Allelic Composition: Krt71Mhdarco12/Krt71+
Genetic Background: C3HeB/FeJ-Krt71Mhdarco12

Allelic Composition: Krt71Mhdarco13/Krt71Mhdarco13
Genetic Background: C3HeB/FeJ-Krt71Mhdarco13

Allelic Composition: Krt71Mhdarco13/Krt71+
Genetic Background: C3HeB/FeJ-Krt71Mhdarco13

Allelic Composition: Hag/Hag+,Krt71Ca/Krt71+
Genetic Background: involves: C3H/HeN * C57BL/6ByJ

Allelic Composition: Krt71Ca/Krt71Ca
Genetic Background: Not Specified

Allelic Composition: Krt71Ca/Krt71+
Genetic Background: Not Specified

Allelic Composition: Krt71Ca-Rin/?
Genetic Background: C57BL/6Slc-Krt71Ca-Rin

Allelic Composition: Krt71Ca-d/Krt71Ca-d
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Krt71Ca-d/Krt71+
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Krt71Ca-7J/Krt71Ca-7J
Genetic Background: involves: BALB/cJ

Allelic Composition: Krt71Ca-17J/Krt71+
Genetic Background: C57BL/6J-Krt71Ca-17J/GrsrJ

Allelic Composition: Krt71Ca-2H/Krt71Ca-2H
Genetic Background: involves: 101/H

Allelic Composition: Krt71Ca/Krt71Ca-2H
Genetic Background: involves: 101/H

Allelic Composition: Krt71Ca-7J/Krt71+
Genetic Background: involves: BALB/cJ

Allelic Composition: Krt71Ca-8J/Krt71Ca-8J
Genetic Background: involves: DBA/2J

Allelic Composition: Krt71Ca-8J/Krt71+
Genetic Background: involves: DBA/2J

Allelic Composition: Krt71Ca-J/Krt71+
Genetic Background: C57BL/6J-Krt71Ca-J

Allelic Composition: Krt71Ca-14J/Krt71+
Genetic Background: involves: BALB/cByJ

Allelic Composition: Krt71Ca-15J/Krt71+
Genetic Background: involves: C57BL/6J

Allelic Composition: Krt71Ca-J/Krt71Ca-J
Genetic Background: C57BL/6J-Krt71Ca-J

Allelic Composition: Krt71Ca-14J/Krt71Ca-14J
Genetic Background: involves: BALB/cByJ

Allelic Composition: Krt71Ca-15J/Krt71Ca-15J
Genetic Background: involves: C57BL/6J

Allelic Composition: Krt71Ca-18J/Krt71+
Genetic Background: NOD/ShiLtJ-Krt71Ca-18J/GrsrJ

Allelic Composition: Krt71Ca-19J/Krt71+
Genetic Background: BALB/cJ-Krt71Ca-19J/GrsrJ

 MP:0000414 alopecia "absence of hair or loss of hair; not usually in reference to primary genetic hairlessness but may be due to dietary, stress, secondary to immune condition" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:30772, J:33796]
Show

Allelic Composition: Krt71rco3/Krt71rco3
Genetic Background: C3HeB/FeJ-Krt71rco3

 MP:0000418 patchy hair "uneven spots of hair growth on the body" [J:26975]
Show

Allelic Composition: Plce1tm1Avsm/Plce1tm1Avsm
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Krt71Ca-d/Krt71Ca-d
Genetic Background: involves: 101/H * C3H/HeH

 MP:0000652 enlarged sebaceous gland "increased size of the sebum secreting glands of the hair shaft" [J:30249]
Show

Allelic Composition: Krt71Ca-Rin/?
Genetic Background: C57BL/6Slc-Krt71Ca-Rin

 MP:0001199 thin skin "reduced thickness of the outer protective layer of the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49471]
Show

Allelic Composition: Krt71Ca-Rin/?
Genetic Background: C57BL/6Slc-Krt71Ca-Rin

 MP:0001274 curly vibrissae "whiskers twisted into coils or spirals" [J:47620]
Show

Allelic Composition: Ccr8tm1Gma/Ccr8tm1Gma
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

Allelic Composition: Krt71rco3/Krt71rco3
Genetic Background: C3HeB/FeJ-Krt71rco3

Allelic Composition: Krt71Rgsc689/?
Genetic Background: involves: C57BL/6J * DBA/2J

Allelic Composition: Krt71Cal4/?
Genetic Background: C57BL/6J-Krt71Cal4/GrsrJ

Allelic Composition: Krt71Mhdarco12/Krt71Mhdarco12
Genetic Background: C3HeB/FeJ-Krt71Mhdarco12

Allelic Composition: Krt71Mhdarco12/Krt71+
Genetic Background: C3HeB/FeJ-Krt71Mhdarco12

Allelic Composition: Krt71Mhdarco13/Krt71Mhdarco13
Genetic Background: C3HeB/FeJ-Krt71Mhdarco13

Allelic Composition: Krt71Mhdarco13/Krt71+
Genetic Background: C3HeB/FeJ-Krt71Mhdarco13

Allelic Composition: Krt71Ca/Krt71Ca
Genetic Background: Not Specified

Allelic Composition: Krt71Ca/Krt71+
Genetic Background: Not Specified

Allelic Composition: Krt71Ca-d/Krt71Ca-d
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Krt71Ca-d/Krt71+
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Krt71Ca-7J/Krt71Ca-7J
Genetic Background: involves: BALB/cJ

Allelic Composition: Krt71Ca-17J/Krt71+
Genetic Background: C57BL/6J-Krt71Ca-17J/GrsrJ

Allelic Composition: Krt71Ca-2H/Krt71Ca-2H
Genetic Background: involves: 101/H

Allelic Composition: Krt71Ca/Krt71Ca-2H
Genetic Background: involves: 101/H

Allelic Composition: Krt71Ca-7J/Krt71+
Genetic Background: involves: BALB/cJ

Allelic Composition: Krt71Ca-8J/Krt71Ca-8J
Genetic Background: involves: DBA/2J

Allelic Composition: Krt71Ca-8J/Krt71+
Genetic Background: involves: DBA/2J

Allelic Composition: Krt71Ca-J/Krt71+
Genetic Background: C57BL/6J-Krt71Ca-J

Allelic Composition: Krt71Ca-14J/Krt71+
Genetic Background: involves: BALB/cByJ

Allelic Composition: Krt71Ca-15J/Krt71+
Genetic Background: involves: C57BL/6J

Allelic Composition: Krt71Ca-J/Krt71Ca-J
Genetic Background: C57BL/6J-Krt71Ca-J

Allelic Composition: Krt71Ca-14J/Krt71Ca-14J
Genetic Background: involves: BALB/cByJ

Allelic Composition: Krt71Ca-15J/Krt71Ca-15J
Genetic Background: involves: C57BL/6J

Allelic Composition: Krt71Ca-18J/Krt71+
Genetic Background: NOD/ShiLtJ-Krt71Ca-18J/GrsrJ

Allelic Composition: Krt71Ca-19J/Krt71+
Genetic Background: BALB/cJ-Krt71Ca-19J/GrsrJ

 MP:0001510 abnormal coat appearance "coat that looks different from the usual state " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Krt71Ca-d/Krt71Ca-d
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Krt71Ca-d/Krt71+
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Krt71Ca-7J/Krt71Ca-7J
Genetic Background: involves: BALB/cJ

Allelic Composition: Krt71Ca-7J/Krt71+
Genetic Background: involves: BALB/cJ

Allelic Composition: Krt71Ca-8J/Krt71Ca-8J
Genetic Background: involves: DBA/2J

Allelic Composition: Krt71Ca-8J/Krt71+
Genetic Background: involves: DBA/2J

Allelic Composition: Krt71Ca-J/Krt71+
Genetic Background: C57BL/6J-Krt71Ca-J

Allelic Composition: Krt71Ca-J/Krt71Ca-J
Genetic Background: C57BL/6J-Krt71Ca-J

Allelic Composition: Krt71Ca-14J/Krt71Ca-14J
Genetic Background: involves: BALB/cByJ

Allelic Composition: Krt71Ca-15J/Krt71Ca-15J
Genetic Background: involves: C57BL/6J

 MP:0002098 abnormal vibrissae morphology "irregular or unusual structure, appearance, or alignment of the vibrissae" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Mcoln3Va-J/Mcoln3+
Genetic Background: B6C3Fe-a/a Hoxa13Hd Mcoln3Va-J/J

Allelic Composition: Krt71Ca-7J/Krt71+
Genetic Background: involves: BALB/cJ

Allelic Composition: Krt71Ca-8J/Krt71Ca-8J
Genetic Background: involves: DBA/2J

Allelic Composition: Krt71Ca-8J/Krt71+
Genetic Background: involves: DBA/2J

 MP:0003809 abnormal hair shaft morphology "irregular or unusual structure of the cuticle, and/or cortex and/or medulla of a hair" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
Show

Allelic Composition: Krt71rco3/Krt71rco3
Genetic Background: C3HeB/FeJ-Krt71rco3

 MP:0003811 abnormal hair cortex "anomalies in the spindle shaped cells of the hair shaft that contains keratin fibrils and matrix" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
Show

Allelic Composition: Krt71rco3/Krt71rco3
Genetic Background: C3HeB/FeJ-Krt71rco3

 MP:0003849 greasy coat "fur is oily in appearance or texture" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
Show

Allelic Composition: Krt71Ca-Rin/?
Genetic Background: C57BL/6Slc-Krt71Ca-Rin

 MP:0008844 decreased subcutaneous adipose tissue amount "reduction in amount of adipose tissue beneath the skin" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Krt71Ca-Rin/?
Genetic Background: C57BL/6Slc-Krt71Ca-Rin

 MP:0009457 whorled hair "an area of hair growing opposite in direction to the rest of the hair, a curl or swirl" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Krt71Ca-d/Krt71Ca-d
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: Krt71Ca-d/Krt71+
Genetic Background: involves: 101/H * C3H/HeH

 MP:0010179 rough coat "coat does not have the usual smooth appearance" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Krt71Ca-Rin/?
Genetic Background: C57BL/6Slc-Krt71Ca-Rin

 MP:0010202 focal dorsal hair loss "focal hair loss on the dorsal area of a rodent resulting in dorsal skin visible in a patch where hair loss occurs" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", MGI:Sanger_Karp "Submission from Natasha Karp"]
Show

Allelic Composition: Krt71rco3/Krt71rco3
Genetic Background: C3HeB/FeJ-Krt71rco3

 MP:0010685 abnormal hair follicle inner root sheath morphology "any structural anomaly of the multilayered tube composed of terminally differentiated hair follicle keratinocytes that is surrounded by the outer root sheath; the layers of the inner root sheath include the companion layer, Henle s layer, Huxley s layer and the inner root sheath cuticle" [PMID:19211055]
Show

Allelic Composition: Krt71rco3/Krt71rco3
Genetic Background: C3HeB/FeJ-Krt71rco3

Allelic Composition: Krt71Mhdarco12/Krt71Mhdarco12
Genetic Background: C3HeB/FeJ-Krt71Mhdarco12

Allelic Composition: Krt71Mhdarco12/Krt71+
Genetic Background: C3HeB/FeJ-Krt71Mhdarco12

Allelic Composition: Krt71Mhdarco13/Krt71Mhdarco13
Genetic Background: C3HeB/FeJ-Krt71Mhdarco13

Allelic Composition: Krt71Mhdarco13/Krt71+
Genetic Background: C3HeB/FeJ-Krt71Mhdarco13

Allelic Composition: Krt71Ca-Rin/?
Genetic Background: C57BL/6Slc-Krt71Ca-Rin

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr