ENSMUSG00000052310


Mus musculus

Features
Gene ID: ENSMUSG00000052310
  
Biological name :Slc39a1
  
Synonyms : Q9QZ03 / Slc39a1 / Zinc transporter ZIP1
  
Possible biological names infered from orthology : Q9NY26 / solute carrier family 39 member 1
  
Species: Mus musculus
  
Chr. number: 3
Strand: 1
Band: F1
Gene start: 90248172
Gene end: 90253612
  
Corresponding Affymetrix probe sets: 10470948 (MoGene1.0st)   10493709 (MoGene1.0st)   1424424_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000076012
NCBI entrez gene - 30791     See in Manteia.
MGI - MGI:1353474
RefSeq - NM_013901
RefSeq - XM_006501560
RefSeq Peptide - NP_038929
swissprot - Q9QZ03
Ensembl - ENSMUSG00000052310
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SLC39A1ENSGALG00000029687Gallus gallus
 Q9NY26ENSG00000143570Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Slc39a2 / solute carrier family 39 member 2 / Q9NP94*ENSMUSG0000007257234
Q99K24 / Slc39a3 / Mus musculus solute carrier family 39 (zinc transporter), member 3 (Slc39a3), transcript variant 2, mRNA. / Q9BRY0* / solute carrier family 39 member 3*ENSMUSG0000004682230


Protein motifs (from Interpro)
Interpro ID Name
 IPR003689  Zinc/iron permease


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001701 in utero embryonic development IMP
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006829 zinc ion transport IEA
 biological_processGO:0030001 metal ion transport IEA
 biological_processGO:0048701 embryonic cranial skeleton morphogenesis IMP
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0060173 limb development IMP
 biological_processGO:0071577 zinc ion transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane IBA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005385 zinc ion transmembrane transporter activity IDA
 molecular_functionGO:0046873 metal ion transmembrane transporter activity IEA


Pathways (from Reactome)
Pathway description
Zinc influx into cells by the SLC39 gene family


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001208 blistering "accumulation of fluid- filled thin walled structures under the epidermis or within the epidermis" [J:65039]
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Allelic Composition: Slc39a1tm1.1Gka/Slc39a1tm1.1Gka,Slc39a3tm1.1Gka/Slc39a3tm1.1Gka
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N

 MP:0001672 abnormal embryogenesis/ development "anomaly in the establishment of the characteristic configuration of the embryonic body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Gasttm1Lcs/Gast+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Slc39a1tm1.1Gka/Slc39a1tm1.1Gka,Slc39a3tm1.1Gka/Slc39a3tm1.1Gka
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Leprtm5Mgmj/Leprtm5Mgmj
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0003935 abnormal craniofacial development "anomaly in the process of forming the face and/or cranium" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gasttm1Lcs/Gast+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Slc39a1tm1.1Gka/Slc39a1tm1.1Gka,Slc39a3tm1.1Gka/Slc39a3tm1.1Gka
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N

 MP:0003984 embryonic growth retardation "slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Gasttm1Lcs/Gast+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Slc39a1tm1.1Gka/Slc39a1tm1.1Gka,Slc39a3tm1.1Gka/Slc39a3tm1.1Gka
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N

 MP:0006279 abnormal limb development "anomaly in the formation of the limbs" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Gasttm1Lcs/Gast+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Slc39a1tm1.1Gka/Slc39a1tm1.1Gka,Slc39a3tm1.1Gka/Slc39a3tm1.1Gka
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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