ENSMUSG00000053286


Mus musculus

Features
Gene ID: ENSMUSG00000053286
  
Biological name :Trmt1l
  
Synonyms : Mus musculus tRNA methyltransferase 1 like (Trmt1l), transcript variant 3, mRNA. / Trmt1l
  
Possible biological names infered from orthology : Q7Z2T5 / tRNA methyltransferase 1 like
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: G1
Gene start: 151428542
Gene end: 151458161
  
Corresponding Affymetrix probe sets: 10350614 (MoGene1.0st)   1426879_at (Mouse Genome 430 2.0 Array)   1447369_at (Mouse Genome 430 2.0 Array)   1456996_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000140009
Ensembl peptide - ENSMUSP00000068309
NCBI entrez gene - 98685     See in Manteia.
MGI - MGI:1916185
RefSeq - XM_017313056
RefSeq - NM_001357570
RefSeq - NM_026876
RefSeq - XM_006529976
RefSeq Peptide - NP_001344499
RefSeq Peptide - NP_081152
swissprot - A0A0R4J0U8
swissprot - A0A087WQ23
Ensembl - ENSMUSG00000053286
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 trmt1lENSDARG00000042057Danio rerio
 TRMT1LENSGALG00000033077Gallus gallus
 Q7Z2T5ENSG00000121486Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Trmt1 / tRNA methyltransferase 1 / Q9NXH9*ENSMUSG0000000190914


Protein motifs (from Interpro)
Interpro ID Name
 IPR002905  tRNA methyltransferase, Trm1
 IPR013087  Zinc finger C2H2-type
 IPR029063  S-adenosyl-L-methionine-dependent methyltransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008033 tRNA processing IEA
 biological_processGO:0030488 tRNA methylation IEA
 biological_processGO:0032259 methylation IEA
 molecular_functionGO:0000049 tRNA binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0004809 tRNA (guanine-N2-)-methyltransferase activity IEA
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001405 impaired coordination "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Thtm1Srt/Thtm1Srt,Tyrc/Tyrc
Genetic Background: involves: 129S2/SvPas * C57BL/6J * ICR

 MP:0001417 decreased exploration in new environment "less amount of time spent investigating a new location" [J:79870]
Show

Allelic Composition: Thtm1Srt/Thtm1Srt,Tyrc/Tyrc
Genetic Background: involves: 129S2/SvPas * C57BL/6J * ICR

 MP:0002757 reduced vertical activity "lesser than average time spent jumping or rearing" [J:82829, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Thtm1Srt/Thtm1Srt,Tyrc/Tyrc
Genetic Background: involves: 129S2/SvPas * C57BL/6J * ICR

 MP:0010053 decreased grip strength "reduced ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]
Show

Allelic Composition: Thtm1Srt/Thtm1Srt,Tyrc/Tyrc
Genetic Background: involves: 129S2/SvPas * C57BL/6J * ICR

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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