ENSMUSG00000001909


Mus musculus

Features
Gene ID: ENSMUSG00000001909
  
Biological name :Trmt1
  
Synonyms : Trmt1 / tRNA methyltransferase 1
  
Possible biological names infered from orthology : Q9NXH9
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: C2
Gene start: 84686307
Gene end: 84699808
  
Corresponding Affymetrix probe sets: 10573401 (MoGene1.0st)   10341241 (MoGene1.0st)   1436494_x_at (Mouse Genome 430 2.0 Array)   1437314_a_at (Mouse Genome 430 2.0 Array)   1451249_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000135327
Ensembl peptide - ENSMUSP00000135273
Ensembl peptide - ENSMUSP00000135510
Ensembl peptide - ENSMUSP00000135680
Ensembl peptide - ENSMUSP00000135675
Ensembl peptide - ENSMUSP00000135540
Ensembl peptide - ENSMUSP00000001974
Ensembl peptide - ENSMUSP00000105389
Ensembl peptide - ENSMUSP00000105390
Ensembl peptide - ENSMUSP00000116712
Ensembl peptide - ENSMUSP00000117140
Ensembl peptide - ENSMUSP00000122526
Ensembl peptide - ENSMUSP00000134723
NCBI entrez gene - 212528     See in Manteia.
MGI - MGI:1289155
RefSeq - XM_017312645
RefSeq - NM_001164559
RefSeq - NM_001164560
RefSeq - NM_198020
RefSeq - XM_006530811
RefSeq - XM_006530812
RefSeq - XM_006530813
RefSeq - XM_006530815
RefSeq - XM_017312644
RefSeq Peptide - NP_001158031
RefSeq Peptide - NP_932137
RefSeq Peptide - NP_001158032
swissprot - A0A0R4IZW7
swissprot - E9PWD4
swissprot - D6RG86
swissprot - D6RFC0
swissprot - G3V019
swissprot - H3BK68
swissprot - H3BKB8
swissprot - H3BKS8
swissprot - H3BL70
swissprot - H3BKV3
swissprot - H3BL74
swissprot - D3Z413
Ensembl - ENSMUSG00000001909
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 trmt1ENSDARG00000010978Danio rerio
 TRMT1ENSG00000104907Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Trmt1l / Mus musculus tRNA methyltransferase 1 like (Trmt1l), transcript variant 3, mRNA. / Q7Z2T5* / tRNA methyltransferase 1 like*ENSMUSG0000005328616


Protein motifs (from Interpro)
Interpro ID Name
 IPR000571  Zinc finger, CCCH-type
 IPR002905  tRNA methyltransferase, Trm1
 IPR029063  S-adenosyl-L-methionine-dependent methyltransferase
 IPR036855  Zinc finger, CCCH-type superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008033 tRNA processing IEA
 biological_processGO:0030488 tRNA methylation IEA
 biological_processGO:0032259 methylation IEA
 molecular_functionGO:0000049 tRNA binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0004809 tRNA (guanine-N2-)-methyltransferase activity IEA
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Tmod2tm1b(KOMP)Wtsi/Tmod2tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Tmod2tm1b(KOMP)Wtsi/J

 MP:0010052 increased grip strength "greater ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]
Show

Allelic Composition: Tmem100tm1e.1(KOMP)Wtsi/Tmem100tm1e.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Tmem100tm1e.1(KOMP)Wtsi/Tcp

 MP:0010053 decreased grip strength "reduced ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]
Show

Allelic Composition: Tmem100tm1e.1(KOMP)Wtsi/Tmem100tm1e.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Tmem100tm1e.1(KOMP)Wtsi/Tcp

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Tmod2tm1b(KOMP)Wtsi/Tmod2tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Tmod2tm1b(KOMP)Wtsi/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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