ENSMUSG00000054934


Mus musculus

Features
Gene ID: ENSMUSG00000054934
  
Biological name :Kcnmb4
  
Synonyms : Calcium-activated potassium channel subunit beta-4 / Kcnmb4 / Q9JIN6
  
Possible biological names infered from orthology : potassium calcium-activated channel subfamily M regulatory beta subunit 4 / Q86W47
  
Species: Mus musculus
  
Chr. number: 10
Strand: -1
Band: D2
Gene start: 116417861
Gene end: 116473878
  
Corresponding Affymetrix probe sets: 10372528 (MoGene1.0st)   1449471_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000065384
NCBI entrez gene - 58802     See in Manteia.
MGI - MGI:1913272
RefSeq - NM_021452
RefSeq Peptide - NP_067427
swissprot - Q9JIN6
Ensembl - ENSMUSG00000054934
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KCNMB4ENSGALG00000010044Gallus gallus
 KCNMB4ENSG00000135643Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Kcnmb2 / Q9CZM9 / Calcium-activated potassium channel subunit beta-2 / Q9Y691* / AC117457.1* / potassium calcium-activated channel subfamily M regulatory beta subunit 2*ENSMUSG0000003761030
Kcnmb3 / potassium calcium-activated channel subfamily M regulatory beta subunit 3 / Q9NPA1*ENSMUSG0000009109127
Kcnmb1 / potassium calcium-activated channel subfamily M regulatory beta subunit 1 / Q16558*ENSMUSG0000002015519


Protein motifs (from Interpro)
Interpro ID Name
 IPR003930  Potassium channel, calcium-activated, BK, beta subunit


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001508 action potential IEA
 biological_processGO:0005513 detection of calcium ion IEA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport ISO
 biological_processGO:0007268 chemical synaptic transmission IBA
 biological_processGO:0019228 neuronal action potential IEA
 biological_processGO:0065009 regulation of molecular function IEA
 biological_processGO:0071805 potassium ion transmembrane transport IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0008076 voltage-gated potassium channel complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005267 potassium channel activity ISS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015269 calcium-activated potassium channel activity ISS
 molecular_functionGO:0015459 potassium channel regulator activity IBA


Pathways (from Reactome)
Pathway description
Ca2+ activated K+ channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000948 nonconvulsive seizures "seizures without uncontrolled motor activity, but with impairment of consciousness" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Tgif1tm1Dwot/Tgif1+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Dgat2tm1Lex/Dgat2tm1Lex
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J

 MP:0005402 abnormal action potential "change in the electric response of a nerve or other excitable tissue to its stimulation" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Tgif1tm1Dwot/Tgif1+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000020155 Kcnmb1 / potassium calcium-activated channel subfamily M regulatory beta subunit 1 / Q16558*  / complex
 ENSMUSG00000054934 Kcnmb4 / Q9JIN6 / Calcium-activated potassium channel subunit beta-4 / Q86W47* / potassium calcium-activated channel subfamily M regulatory beta subunit 4*  / complex
 ENSMUSG00000037610 Kcnmb2 / Q9CZM9 / Calcium-activated potassium channel subunit beta-2 / Q9Y691* / AC117457.1* / potassium calcium-activated channel subfamily M regulatory beta subunit 2*  / complex
 ENSMUSG00000091091 Kcnmb3 / potassium calcium-activated channel subfamily M regulatory beta subunit 3 / Q9NPA1*  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr