ENSMUSG00000056076


Mus musculus

Features
Gene ID: ENSMUSG00000056076
  
Biological name :Eif3b
  
Synonyms : Eif3b / Eukaryotic translation initiation factor 3 subunit B / Q8JZQ9
  
Possible biological names infered from orthology : P55884
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: G2
Gene start: 140419328
Gene end: 140443360
  
Corresponding Affymetrix probe sets: 10526977 (MoGene1.0st)   1426674_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000143425
Ensembl peptide - ENSMUSP00000098076
NCBI entrez gene - 27979     See in Manteia.
MGI - MGI:106478
RefSeq - NM_133916
RefSeq Peptide - NP_598677
swissprot - A0A0G2JG48
swissprot - Q8JZQ9
Ensembl - ENSMUSG00000056076
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 eif3baENSDARG00000059654Danio rerio
 eif3bbENSDARG00000074213Danio rerio
 EIF3BENSGALG00000040999Gallus gallus
 EIF3BENSG00000106263Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR011400  Eukaryotic translation initiation factor 3 subunit B
 IPR013979  Translation initiation factor, beta propellor-like domain
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR034363  eIF3B, RNA recognition motif
 IPR035979  RNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006412 translation IEA
 biological_processGO:0006413 translational initiation IEA
 biological_processGO:0006446 regulation of translational initiation IEA
 biological_processGO:0075522 IRES-dependent viral translational initiation IEA
 biological_processGO:0075525 viral translational termination-reinitiation IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005852 eukaryotic translation initiation factor 3 complex IEA
 cellular_componentGO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003743 translation initiation factor activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0031369 translation initiation factor binding IEA


Pathways (from Reactome)
Pathway description
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011094 complete embryonic lethality before implantation "death of all organisms of a given genotype in a population between fertilization and implantation (Mus: E0 to less than E4.5)" [MGI:csmith]
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Allelic Composition: Dok7tm2Yyam/Dok7tm2Yyam
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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