ENSMUSG00000056228


Mus musculus

Features
Gene ID: ENSMUSG00000056228
  
Biological name :Cars2
  
Synonyms : Cars2 / cysteinyl-tRNA synthetase 2 (mitochondrial)(putative)
  
Possible biological names infered from orthology : cysteinyl-tRNA synthetase 2, mitochondrial / Q9HA77
  
Species: Mus musculus
  
Chr. number: 8
Strand: -1
Band: A1.1
Gene start: 11513977
Gene end: 11550783
  
Corresponding Affymetrix probe sets: 10577030 (MoGene1.0st)   1428524_at (Mouse Genome 430 2.0 Array)   1431778_at (Mouse Genome 430 2.0 Array)   1454186_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000148102
Ensembl peptide - ENSMUSP00000046453
Ensembl peptide - ENSMUSP00000147421
Ensembl peptide - ENSMUSP00000147495
Ensembl peptide - ENSMUSP00000148016
NCBI entrez gene - 71941     See in Manteia.
MGI - MGI:1919191
RefSeq - XM_011242082
RefSeq - NM_001359137
RefSeq - NM_024248
RefSeq - XM_006508890
RefSeq - XM_006508893
RefSeq - XM_006508898
RefSeq - XM_011242081
RefSeq Peptide - NP_077210
RefSeq Peptide - NP_001346066
swissprot - A0A1B0GSP2
swissprot - A0A1B0GRF1
swissprot - A0A1B0GR87
swissprot - G3X975
swissprot - A0A1B0GSW7
Ensembl - ENSMUSG00000056228
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cars2ENSDARG00000078546Danio rerio
 CARS2ENSGALG00000016847Gallus gallus
 CARS2ENSG00000134905Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cars / Q9ER72 / Cysteine--tRNA ligase, cytoplasmic / P49589* / cysteinyl-tRNA synthetase*ENSMUSG0000001075534


Protein motifs (from Interpro)
Interpro ID Name
 IPR009080  Aminoacyl-tRNA synthetase, class Ia, anticodon-binding
 IPR014729  Rossmann-like alpha/beta/alpha sandwich fold
 IPR015803  Cysteine-tRNA ligase
 IPR024909  Cysteinyl-tRNA synthetase/mycothiol ligase
 IPR032678  tRNA synthetases class I, catalytic domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006418 tRNA aminoacylation for protein translation IEA
 biological_processGO:0006423 cysteinyl-tRNA aminoacylation IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004812 aminoacyl-tRNA ligase activity IEA
 molecular_functionGO:0004817 cysteine-tRNA ligase activity IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000745 tremors "repetitive, cyclical movements of the body or a body part; usually involuntary, but can also manifest in response to an attempt at movement" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Lmnatm3Lgf/Lmnatm3Lgf
Genetic Background: involves: 129P2/OlaHsd

 MP:0001410 head bobbing "compulsive up and down movement of the head" [J:17123]
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Allelic Composition: Lmnatm3Lgf/Lmnatm3Lgf
Genetic Background: involves: 129P2/OlaHsd

 MP:0008911 induced hyperactivity "increased physical activity following stimulation such as handling, touching or noise" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Lmnatm3Lgf/Lmnatm3Lgf
Genetic Background: involves: 129P2/OlaHsd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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