| MP:0000042 | abnormal organ of Corti | "abnormalities associated with the highly specialized epithelium in the floor of the ductus cochlearis; also referred to a spiral organ (organum spirale), or acoustic papilla" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Nkx2-5tm2.1Mwc/Nkx2-5+
Genetic Background: B6J.Cg-Nkx2-5tm2.1Mwc/Mwc
Allelic Composition: Slc44a2tm1.2Tec/Slc44a2+
Genetic Background: FVB.129(Cg)-Slc44a2tm1.2Tec
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| MP:0001265 | reduced body size | "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170] |
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Allelic Composition: Nkx2-5tm2.1Mwc/Nkx2-5+
Genetic Background: B6J.Cg-Nkx2-5tm2.1Mwc/Mwc
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| MP:0002169 | no phenotype detected | "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Nkx2-5tm2.1Mwc/Nkx2-5+
Genetic Background: B6J.Cg-Nkx2-5tm2.1Mwc/Mwc
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| MP:0002855 | abnormal cochlear ganglion morphology | "malformation, malfunction or absence of the group of nerve cell bodies that conveys auditory sensation from the organ of Corti to the hindbrain and resides on the cochlear part of the vestibulocochlear nerve (eighth cranial nerve)" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Nkx2-5tm2.1Mwc/Nkx2-5+
Genetic Background: B6J.Cg-Nkx2-5tm2.1Mwc/Mwc
Allelic Composition: Slc44a2tm1.2Tec/Slc44a2+
Genetic Background: FVB.129(Cg)-Slc44a2tm1.2Tec
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| MP:0004396 | decreased cochlear inner hair cell number | "decreased number (or less than the expected single row) of the flask-shaped inner hair sensory cells of the organ of Corti" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Nkx2-5tm2.1Mwc/Nkx2-5+
Genetic Background: B6J.Cg-Nkx2-5tm2.1Mwc/Mwc
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| MP:0004402 | decreased cochlear outer hair cell number | "decreased number (or less than the expected 3 rows) of the columnar outer hair sensory cells of the organ of Corti" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Nkx2-5tm2.1Mwc/Nkx2-5+
Genetic Background: B6J.Cg-Nkx2-5tm2.1Mwc/Mwc
Allelic Composition: Slc44a2tm1.2Tec/Slc44a2+
Genetic Background: FVB.129(Cg)-Slc44a2tm1.2Tec
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| MP:0004740 | sensorineural hearing loss | "a form of progressive hearing loss due to a lesion of the auditory division of cranial nerve VIII or the inner ear" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Nkx2-5tm2.1Mwc/Nkx2-5+
Genetic Background: B6J.Cg-Nkx2-5tm2.1Mwc/Mwc
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| MP:0004748 | increased susceptibility to age-related hearing loss | "greater than normal loss of hearing associated with advancing age, manifest as reduced ability to perceive or discriminate sounds; the pattern and age of onset vary" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Nkx2-5tm2.1Mwc/Nkx2-5+
Genetic Background: B6J.Cg-Nkx2-5tm2.1Mwc/Mwc
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| MP:0011967 | increased or absent threshold for auditory brainstem response | "increase in the value at which one or more sound frequencies or broadband clicks first elicits a recordable response generated by electrical activity of neurons in the ascending auditory system, or complete lack of a recordable response at any frequency or broadband click" [MGI:csmith] |
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Allelic Composition: Nkx2-5tm2.1Mwc/Nkx2-5+
Genetic Background: B6J.Cg-Nkx2-5tm2.1Mwc/Mwc
Allelic Composition: Slc44a2tm1.2Tec/Slc44a2+
Genetic Background: FVB.129(Cg)-Slc44a2tm1.2Tec
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| MP:0013808 | abnormal tunnel of Corti morphology | "any structrual anomaly of the triangular, fluid-filled space normally found between the inner and outer rows of supporting pillar cells in the organ of Corti" [MGI:Anna] |
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Allelic Composition: Nkx2-5tm2.1Mwc/Nkx2-5+
Genetic Background: B6J.Cg-Nkx2-5tm2.1Mwc/Mwc
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