ENSMUSG00000028412


Mus musculus

Features
Gene ID: ENSMUSG00000028412
  
Biological name :Slc44a1
  
Synonyms : Q6X893 / Slc44a1 / solute carrier family 44, member 1
  
Possible biological names infered from orthology : Q8WWI5
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: B2
Gene start: 53440413
Gene end: 53622478
  
Corresponding Affymetrix probe sets: 10505008 (MoGene1.0st)   10505028 (MoGene1.0st)   1423865_at (Mouse Genome 430 2.0 Array)   1432769_at (Mouse Genome 430 2.0 Array)   1433645_at (Mouse Genome 430 2.0 Array)   1454344_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000103272
Ensembl peptide - ENSMUSP00000103278
Ensembl peptide - ENSMUSP00000103274
Ensembl peptide - ENSMUSP00000103273
Ensembl peptide - ENSMUSP00000099975
NCBI entrez gene - 100434     See in Manteia.
MGI - MGI:2140592
RefSeq - XM_006537531
RefSeq - XM_017319900
RefSeq - XM_006537533
RefSeq - XM_006537532
RefSeq - NM_001159633
RefSeq - NM_133891
RefSeq Peptide - NP_001153105
RefSeq Peptide - NP_598652
swissprot - Q6X893
swissprot - A2AMH8
swissprot - A2AMH3
swissprot - A2AMH4
swissprot - A2AMH5
Ensembl - ENSMUSG00000028412
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc44a1aENSDARG00000015946Danio rerio
 slc44a1bENSDARG00000090982Danio rerio
 SLC44A1ENSGALG00000015439Gallus gallus
 Q8WWI5ENSG00000070214Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q921V7 / Slc44a3 / solute carrier family 44, member 3 / Q8N4M1*ENSMUSG0000003986546
Q91VA1 / Slc44a4 / solute carrier family 44, member 4 / Q53GD3*ENSMUSG0000000703428
Q8BY89 / Slc44a2 / solute carrier family 44, member 2 / Q8IWA5*ENSMUSG0000005719327
Q5RJI2 / Slc44a5 / solute carrier family 44, member 5 / Q8NCS7*ENSMUSG0000002836024


Protein motifs (from Interpro)
Interpro ID Name
 IPR007603  Choline transporter-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0015871 choline transport IDA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005741 mitochondrial outer membrane IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0015220 choline transmembrane transporter activity IDA


Pathways (from Reactome)
Pathway description
Synthesis of PC
Transport of bile salts and organic acids, metal ions and amine compounds
Choline catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001399 hyperactivity "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]
Show

Allelic Composition: Mthfd1tm2b(KOMP)Wtsi/Mthfd1tm2b(KOMP)Wtsi
Genetic Background: C57BL/6N-Mthfd1tm2b(KOMP)Wtsi/Bay

 MP:0001415 increased exploration in new environment "greater amount of time spent investigating new location" [J:28825]
Show

Allelic Composition: Mthfd1tm2b(KOMP)Wtsi/Mthfd1tm2b(KOMP)Wtsi
Genetic Background: C57BL/6N-Mthfd1tm2b(KOMP)Wtsi/Bay

 MP:0001510 abnormal coat appearance "coat that looks different from the usual state " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Mthfd1tm2b(KOMP)Wtsi/Mthfd1tm2b(KOMP)Wtsi
Genetic Background: C57BL/6N-Mthfd1tm2b(KOMP)Wtsi/Bay

 MP:0003795 abnormal bone structure 
Show

Allelic Composition: Mthfd1tm2b(KOMP)Wtsi/Mthfd1tm2b(KOMP)Wtsi
Genetic Background: C57BL/6N-Mthfd1tm2b(KOMP)Wtsi/Bay

 MP:0003960 increased lean body mass "more than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator]
Show

Allelic Composition: Mthfd1tm2b(KOMP)Wtsi/Mthfd1tm2b(KOMP)Wtsi
Genetic Background: C57BL/6N-Mthfd1tm2b(KOMP)Wtsi/Bay

 MP:0010025 decreased total body fat amount "less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Mthfd1tm2b(KOMP)Wtsi/Mthfd1tm2b(KOMP)Wtsi
Genetic Background: C57BL/6N-Mthfd1tm2b(KOMP)Wtsi/Bay

 MP:0010123 increased bone mineral content "elevation in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Mthfd1tm2b(KOMP)Wtsi/Mthfd1tm2b(KOMP)Wtsi
Genetic Background: C57BL/6N-Mthfd1tm2b(KOMP)Wtsi/Bay

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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