ENSMUSG00000057561
Mus musculus | |
Features
| Gene ID: | ENSMUSG00000057561 | | | | | Biological name : | Eif1a | | | | | Synonyms : | Eif1a / Eukaryotic translation initiation factor 1A / Q60872 | | | | | Possible biological names infered from orthology : | EIF1AX / eukaryotic translation initiation factor 1A, X-linked / P47813 | | | | | Species: | Mus musculus | | | | | Chr. number: | 18 | | Strand: | 1 | | Band: | C | | Gene start: | 46597704 | | Gene end: | 46610225 | | | | | Corresponding Affymetrix probe sets: | 10455533 (MoGene1.0st) 1424343_a_at (Mouse Genome 430 2.0 Array) 1424344_s_at (Mouse Genome 430 2.0 Array) | | | | | Cross references: | Ensembl peptide - ENSMUSP00000077223
Ensembl peptide - ENSMUSP00000132018
NCBI entrez gene - 13664
See in Manteia.
MGI - MGI:95298
RefSeq - XM_006525626
RefSeq - NM_010120
RefSeq Peptide - NP_034250
swissprot - Q4FJR7
swissprot - Q60872
Ensembl - ENSMUSG00000057561
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See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed
Ortholog prediction (from Ensembl)
Paralog prediction (from Ensembl)
| Eif1ax / Q8BMJ3 / Eukaryotic translation initiation factor 1A, X-chromosomal / P47813* / eukaryotic translation initiation factor 1A, X-linked* | ENSMUSG00000067194 | 99 | | Gm5788 / EIF1AX* / P47813* / eukaryotic translation initiation factor 1A, X-linked* | ENSMUSG00000113805 | 95 | | Gm8300 / EIF1AX* / P47813* / eukaryotic translation initiation factor 1A, X-linked* | ENSMUSG00000079034 | 95 | | Gm8332 / EIF1AX* / P47813* / eukaryotic translation initiation factor 1A, X-linked* | ENSMUSG00000095799 | 95 | | Gm2056 / EIF1AX* / P47813* / eukaryotic translation initiation factor 1A, X-linked* | ENSMUSG00000095717 | 95 | | Gm2035 / EIF1AX* / P47813* / eukaryotic translation initiation factor 1A, X-linked* | ENSMUSG00000096619 | 94 | | Gm2022 / EIF1AX* / P47813* / eukaryotic translation initiation factor 1A, X-linked* | ENSMUSG00000113971 | 94 | | Gm5662 / EIF1AX* / P47813* / eukaryotic translation initiation factor 1A, X-linked* | ENSMUSG00000079029 | 94 | | Gm2016 / EIF1AX* / P47813* / eukaryotic translation initiation factor 1A, X-linked* | ENSMUSG00000072905 | 94 | | Gm5039 / EIF1AX* / P47813* / eukaryotic translation initiation factor 1A, X-linked* | ENSMUSG00000093847 | 94 | | Gm16368 / EIF1AX* / P47813* / eukaryotic translation initiation factor 1A, X-linked* | ENSMUSG00000114075 | 93 | | Gm21319 / EIF1AX* / P47813* / eukaryotic translation initiation factor 1A, X-linked* | ENSMUSG00000095724 | 93 | | Gm21936 / EIF1AX* / P47813* / eukaryotic translation initiation factor 1A, X-linked* | ENSMUSG00000113201 | 93 | | Gm2075 / EIF1AX* / P47813* / eukaryotic translation initiation factor 1A, X-linked* | ENSMUSG00000096049 | 92 | | Gm4027 / EIF1AX* / P47813* / eukaryotic translation initiation factor 1A, X-linked* | ENSMUSG00000092019 | 92 | | Gm6803 / predicted 6803 / EIF1AX* / P47813* / eukaryotic translation initiation factor 1A, X-linked* | ENSMUSG00000096803 | 92 | | BB287469 / expressed sequence BB287469 / EIF1AX* / P47813* / eukaryotic translation initiation factor 1A, X-linked* | ENSMUSG00000079031 | 92 |
Protein motifs (from Interpro)
| IPR001253 | Translation initiation factor 1A (eIF-1A) | | IPR006196 | RNA-binding domain, S1, IF1 type | | IPR012340 | Nucleic acid-binding, OB-fold | | IPR018104 | Translation initiation factor 1A (eIF-1A), conserved site |
Gene Ontology (GO)
Pathways (from Reactome)
Phenotype (from MGI, Zfin or HPO)
| MP:0000929 | open neural tube | "incomplete invagination and fusion of the neuroepithelial layer in early development" [MGI:CLS, J:53370, J:62571] |
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Allelic Composition: Eif1atm1Tcrl/Eif1a+,Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * CBA
| | MP:0003054 | spina bifida | "common congenital midline defect of fusion of the vertebral arch" [MeSH:National Library of Medicine - Medical Subject Headings, 2003] |
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Allelic Composition: Eif1atm1Tcrl/Eif1a+,Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * CBA
| | MP:0005157 | holoprosencephaly | "presence of a single forebrain hemisphere or lobe; often accompanied by a deficit in median facial development" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:83058] |
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Allelic Composition: Eif1atm1Tcrl/Eif1a+,Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * CBA
| | MP:0011085 | complete postnatal lethality | "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
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Allelic Composition: Eif1atm1Tcrl/Eif1a+,Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * CBA
| | MP:0011109 | partial lethality throughout fetal growth and development | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between the completion of organogenesis and birth (Mus: E14 to approximately E18.5)" [MGI:csmith] |
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Allelic Composition: Eif1atm1Tcrl/Eif1a+,Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * CBA
| | MP:0011400 | complete lethality | "all individuals of a given genotype in a population die before the end of the normal lifespan but time(s) of death are unspecified" [MGI:llw2] |
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Allelic Composition: Tlx1tm1.1(cre/ERT2)Rygo/Tlx1tm1.1(cre/ERT2)Rygo
Genetic Background: involves: C57BL/6 * C57BL/6JJcl * C57BL/6NSlc
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Interacting proteins (from Reactome)
No match
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