ENSMUSG00000057880


Mus musculus

Features
Gene ID: ENSMUSG00000057880
  
Biological name :Abat
  
Synonyms : 4-aminobutyrate aminotransferase, mitochondrial / Abat / P61922
  
Possible biological names infered from orthology : 4-aminobutyrate aminotransferase / P80404
  
Species: Mus musculus
  
Chr. number: 16
Strand: 1
Band: A1
Gene start: 8513429
Gene end: 8621568
  
Corresponding Affymetrix probe sets: 10433445 (MoGene1.0st)   1433855_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000121881
Ensembl peptide - ENSMUSP00000063548
Ensembl peptide - ENSMUSP00000111505
Ensembl peptide - ENSMUSP00000111504
Ensembl peptide - ENSMUSP00000116686
NCBI entrez gene - 268860     See in Manteia.
MGI - MGI:2443582
RefSeq - NM_172961
RefSeq - NM_001170978
RefSeq Peptide - NP_001164449
RefSeq Peptide - NP_766549
swissprot - Q3TUE8
swissprot - F6RN86
swissprot - F7C9G3
swissprot - P61922
Ensembl - ENSMUSG00000057880
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 abatENSDARG00000006031Danio rerio
 ABATENSGALG00000007334Gallus gallus
 ABATENSG00000183044Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004631  4-aminobutyrate aminotransferase, eukaryotic
 IPR005814  Aminotransferase class-III
 IPR015421  Pyridoxal phosphate-dependent transferase, major domain
 IPR015422  Pyridoxal phosphate-dependent transferase domain 1
 IPR015424  Pyridoxal phosphate-dependent transferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia IEA
 biological_processGO:0007568 aging IEA
 biological_processGO:0007620 copulation IEA
 biological_processGO:0007626 locomotory behavior IEA
 biological_processGO:0009448 gamma-aminobutyric acid metabolic process IEA
 biological_processGO:0009449 gamma-aminobutyric acid biosynthetic process IEA
 biological_processGO:0010039 response to iron ion IEA
 biological_processGO:0014053 negative regulation of gamma-aminobutyric acid secretion IEA
 biological_processGO:0021549 cerebellum development IEA
 biological_processGO:0031652 positive regulation of heat generation IEA
 biological_processGO:0032024 positive regulation of insulin secretion IEA
 biological_processGO:0033602 negative regulation of dopamine secretion IEA
 biological_processGO:0035094 response to nicotine IEA
 biological_processGO:0035640 exploration behavior IEA
 biological_processGO:0042135 neurotransmitter catabolic process IEA
 biological_processGO:0042220 response to cocaine IEA
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0045471 response to ethanol IEA
 biological_processGO:0045776 negative regulation of blood pressure IEA
 biological_processGO:0045964 positive regulation of dopamine metabolic process IEA
 biological_processGO:0048148 behavioral response to cocaine IMP
 biological_processGO:0070474 positive regulation of uterine smooth muscle contraction IEA
 biological_processGO:0090331 negative regulation of platelet aggregation IEA
 biological_processGO:0097151 positive regulation of inhibitory postsynaptic potential IEA
 biological_processGO:1902722 positive regulation of prolactin secretion IEA
 biological_processGO:1904450 positive regulation of aspartate secretion IEA
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005759 mitochondrial matrix IEA
 cellular_componentGO:0032144 4-aminobutyrate transaminase complex ISO
 cellular_componentGO:0043005 neuron projection IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0003867 4-aminobutyrate transaminase activity IEA
 molecular_functionGO:0008483 transaminase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0030170 pyridoxal phosphate binding IEA
 molecular_functionGO:0032145 succinate-semialdehyde dehydrogenase binding ISS
 molecular_functionGO:0034386 4-aminobutyrate:2-oxoglutarate transaminase activity IEA
 molecular_functionGO:0042803 protein homodimerization activity ISS
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0047298 (S)-3-amino-2-methylpropionate transaminase activity IEA
 molecular_functionGO:0051536 iron-sulfur cluster binding IEA


Pathways (from Reactome)
Pathway description
Degradation of GABA


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000057880 Abat / P61922 / 4-aminobutyrate aminotransferase, mitochondrial / P80404* / 4-aminobutyrate aminotransferase*  / complex






 

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