ENSMUSG00000060671


Mus musculus

Features
Gene ID: ENSMUSG00000060671
  
Biological name :Atp8b2
  
Synonyms : Atp8b2 / P98199 / Phospholipid-transporting ATPase ID
  
Possible biological names infered from orthology : ATPase phospholipid transporting 8B2 / P98198
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: F1
Gene start: 89939481
Gene end: 89963508
  
Corresponding Affymetrix probe sets: 10499666 (MoGene1.0st)   1434026_at (Mouse Genome 430 2.0 Array)   1441699_at (Mouse Genome 430 2.0 Array)   1452450_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000127720
Ensembl peptide - ENSMUSP00000132201
Ensembl peptide - ENSMUSP00000130545
Ensembl peptide - ENSMUSP00000129641
Ensembl peptide - ENSMUSP00000128726
Ensembl peptide - ENSMUSP00000128423
Ensembl peptide - ENSMUSP00000063384
Ensembl peptide - ENSMUSP00000103019
Ensembl peptide - ENSMUSP00000126142
NCBI entrez gene - 54667     See in Manteia.
MGI - MGI:1859660
RefSeq - NM_001081182
RefSeq - XM_006501714
RefSeq - XM_006501715
RefSeq Peptide - NP_001074651
swissprot - F6QLG1
swissprot - F6SPT4
swissprot - E9QAL4
swissprot - P98199
swissprot - F6WT01
swissprot - E9Q8R2
swissprot - E9Q491
swissprot - E9Q114
swissprot - D3YXQ5
Ensembl - ENSMUSG00000060671
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ATP8B2ENSGALG00000034501Gallus gallus
 ATP8B2ENSG00000143515Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Atp8b4 / ATPase, class I, type 8B, member 4 / Q8TF62* / ATPase phospholipid transporting 8B4 (putative)*ENSMUSG0000006013169
A3FIN4 / Atp8b5 / Phospholipid-transporting ATPase FetA ENSMUSG0000002845757
Atp8b1 / Q148W0 / Phospholipid-transporting ATPase IC / O43520* / ATPase phospholipid transporting 8B1*ENSMUSG0000003952954
Atp8a2 / P98200 / Phospholipid-transporting ATPase IB / Q9NTI2* / ATPase phospholipid transporting 8A2*ENSMUSG0000002198338
Atp8a1 / P70704 / Phospholipid-transporting ATPase IA / Q9Y2Q0* / ATPase phospholipid transporting 8A1*ENSMUSG0000003768538
Atp10a / O54827 / Probable phospholipid-transporting ATPase VA / O60312* / ATPase phospholipid transporting 10A (putative)*ENSMUSG0000002532436
Atp11b / ATPase, class VI, type 11B / Q9Y2G3* / ATPase phospholipid transporting 11B (putative)*ENSMUSG0000003740033
Atp11a / P98197 / Probable phospholipid-transporting ATPase IH / P98196* / ATPase phospholipid transporting 11A*ENSMUSG0000003144132
Atp11c / Q9QZW0 / Phospholipid-transporting ATPase 11C / Q8NB49* / ATPase phospholipid transporting 11C*ENSMUSG0000006294931


Protein motifs (from Interpro)
Interpro ID Name
 IPR001757  P-type ATPase
 IPR006539  P-type ATPase, subfamily IV
 IPR008250  P-type ATPase, A domain superfamily
 IPR018303  P-type ATPase, phosphorylation site
 IPR023214  HAD superfamily
 IPR023298  P-type ATPase, transmembrane domain superfamily
 IPR023299  P-type ATPase, cytoplasmic domain N
 IPR030347  Phospholipid-transporting ATPase ID
 IPR032630  P-type ATPase, C-terminal
 IPR032631  P-type ATPase, N-terminal
 IPR036412  HAD-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006869 lipid transport IEA
 biological_processGO:0007030 Golgi organization IBA
 biological_processGO:0015914 phospholipid transport IEA
 biological_processGO:0045332 phospholipid translocation IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004012 phospholipid-translocating ATPase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Ion transport by P-type ATPases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0005419 hypoalbuminemia "blood albumin concentration below the normal range" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Mbpshi-mld/Mbpshi-mld
Genetic Background: MDB/Dt

 MP:0010025 decreased total body fat amount "less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Mbpshi-mld/Mbpshi-mld
Genetic Background: MDB/Dt

 MP:0010123 increased bone mineral content "elevation in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Mbpshi-mld/Mbpshi-mld
Genetic Background: MDB/Dt

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Mbpshi-mld/Mbpshi-mld
Genetic Background: MDB/Dt

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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