ENSMUSG00000062044


Mus musculus

Features
Gene ID: ENSMUSG00000062044
  
Biological name :Lmtk3
  
Synonyms : lemur tyrosine kinase 3 / Lmtk3
  
Possible biological names infered from orthology : Q96Q04
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: B3
Gene start: 45783738
Gene end: 45804144
  
Corresponding Affymetrix probe sets: 10553115 (MoGene1.0st)   1444573_at (Mouse Genome 430 2.0 Array)   1457420_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000072388
Ensembl peptide - ENSMUSP00000148070
Ensembl peptide - ENSMUSP00000148041
Ensembl peptide - ENSMUSP00000148018
Ensembl peptide - ENSMUSP00000147480
Ensembl peptide - ENSMUSP00000147390
Ensembl peptide - ENSMUSP00000112592
NCBI entrez gene - 381983     See in Manteia.
MGI - MGI:3039582
RefSeq - XM_017322327
RefSeq - NM_001005511
RefSeq - NM_001290990
RefSeq - XM_006540961
RefSeq - XM_006540964
RefSeq - XM_006540965
RefSeq - XM_006540966
RefSeq Peptide - NP_001005511
RefSeq Peptide - NP_001277919
swissprot - A0A1B0GRD8
swissprot - A0A1B0GSU1
swissprot - A0A0R4J0W7
swissprot - A0A1B0GSR5
swissprot - A0A1B0GR61
swissprot - A0A1B0GSP4
Ensembl - ENSMUSG00000062044
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LMTK3ENSG00000142235Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Aatk / apoptosis associated tyrosine kinase / Q6ZMQ8*ENSMUSG0000002537531
Lmtk2 / Q3TYD6 / Serine/threonine-protein kinase LMTK2 / Q8IWU2* / lemur tyrosine kinase 2*ENSMUSG0000003897026


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR008266  Tyrosine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Wdr13tm1Kuma/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0001364 decreased anxiety-related response "when compared to controls, subjects exhibit fewer responses thought to be indicative of anxiety in behavioral tests" [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator, J:86626, J:85438, J:64043]
Show

Allelic Composition: Wdr13tm1Kuma/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0001399 hyperactivity "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]
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Allelic Composition: Wdr13tm1Kuma/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0001488 increased startle reflex "reduced threshold or more severe reflex response to variable stimuli, often auditory; usually measured by amplitude of whole body flinch" [What s Wrong With My Mouse?:ISBN 0-471-31639-3, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Wdr13tm1Kuma/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0001764 abnormal homeostasis "anomaly in the state of equilibrium in the body with respect to various functions and to chemical composition of the fluids and tissues" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Wdr13tm1Kuma/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0001921 reduced fertility "diminished ability to produce live offspring" [J:65030]
Show

Allelic Composition: Wdr13tm1Kuma/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0002566 abnormal sexual interaction "altered initiation, failure of initiation or incomplete mating behavior" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Wdr13tm1Kuma/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0002574 increased vertical activity "greater than average time spent jumping or rearing " [J:72576, cwg:Carroll W. Goldsmith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Wdr13tm1Kuma/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0003063 increased coping response "enhanced ability to respond productively to a stressful situation" [RGD:Rat Genome Database submission]
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Allelic Composition: Wdr13tm1Kuma/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0004811 abnormal neuron physiology "anomalous function of the cells of the nervous system that receive, conduct, and transmit impulses" [MESH:National Library of Medicine_Medical Subject Headings]
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Allelic Composition: Wdr13tm1Kuma/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0009746 enhanced behavioral response to xenobiotic "increased sensitivity to a foreign compound capable of inducing the appearance of behavioral response, such as consumption preference, induced hyperactivity or stereotypic behavior, or reduced dosage threshold for the appearance of the behavioral response" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Wdr13tm1Kuma/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0011939 increased food intake "increase in the total number of calories/food amount taken in over time when compared to the normal state" [MGI:csmith]
Show

Allelic Composition: Wdr13tm1Kuma/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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