ENSMUSG00000063663


Mus musculus

Features
Gene ID: ENSMUSG00000063663
  
Biological name :Brwd3
  
Synonyms : A2AHJ4 / Bromodomain and WD repeat-containing protein 3 / Brwd3
  
Possible biological names infered from orthology : bromodomain and WD repeat domain containing 3 / Q6RI45
  
Species: Mus musculus
  
Chr. number: X
Strand: -1
Band: D
Gene start: 108737016
Gene end: 108834372
  
Corresponding Affymetrix probe sets: 10606391 (MoGene1.0st)   10606393 (MoGene1.0st)   1439775_at (Mouse Genome 430 2.0 Array)   1440881_at (Mouse Genome 430 2.0 Array)   1441182_at (Mouse Genome 430 2.0 Array)   1441451_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000098841
Ensembl peptide - ENSMUSP00000123588
Ensembl peptide - ENSMUSP00000133674
Ensembl peptide - ENSMUSP00000134621
NCBI entrez gene - 382236     See in Manteia.
MGI - MGI:3029414
RefSeq - XM_006528114
RefSeq - NM_001081477
RefSeq Peptide - NP_001074946
swissprot - G3UXF9
swissprot - A2AHJ4
swissprot - G3UZT0
Ensembl - ENSMUSG00000063663
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 brwd3ENSDARG00000035540Danio rerio
 BRWD3ENSGALG00000007151Gallus gallus
 BRWD3ENSG00000165288Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Phip / pleckstrin homology domain interacting protein / Q8WWQ0*ENSMUSG0000003225356
Brwd1 / Q921C3 / Bromodomain and WD repeat-containing protein 1 / Q9NSI6* / bromodomain and WD repeat domain containing 1*ENSMUSG0000002291455


Protein motifs (from Interpro)
Interpro ID Name
 IPR001487  Bromodomain
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR036322  WD40-repeat-containing domain superfamily
 IPR036427  Bromodomain-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0007010 cytoskeleton organization ISO
 biological_processGO:0008360 regulation of cell shape ISO
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000433 microcephaly "an abnormally small head" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Tmprss6tm1Dgen/Tmprss6+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129S6/SvEvTac * C57BL/6

 MP:0003984 embryonic growth retardation "slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Tmprss6tm1Dgen/Tmprss6+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129S6/SvEvTac * C57BL/6

 MP:0012062 small tail bud "decreased size or area of the primordial region of the embryo that arises to form the tail of the adult" [MGI:anna]
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Allelic Composition: Tmprss6tm1Dgen/Tmprss6+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129S6/SvEvTac * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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