ENSMUSG00000067071


Mus musculus

Features
Gene ID: ENSMUSG00000067071
  
Biological name :Hes6
  
Synonyms : Hes6 / Q9JHE6 / Transcription cofactor HES-6
  
Possible biological names infered from orthology : hes family bHLH transcription factor 6 / Q96HZ4
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: D
Gene start: 91411483
Gene end: 91414038
  
Corresponding Affymetrix probe sets: 10356593 (MoGene1.0st)   1436050_x_at (Mouse Genome 430 2.0 Array)   1452021_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000084062
NCBI entrez gene - 55927     See in Manteia.
MGI - MGI:1859852
RefSeq - NM_019479
RefSeq - XM_006529759
RefSeq Peptide - NP_062352
swissprot - Q9JHE6
Ensembl - ENSMUSG00000067071
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 her13ENSDARG00000007097Danio rerio
 ENSGALG00000028415Gallus gallus
 HES6ENSG00000144485Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Hes1 / P35428 / Transcription factor HES-1 / Q14469* / hes family bHLH transcription factor 1*ENSMUSG0000002252824
Hes2 / O54792 / Transcription factor HES-2 / Q9Y543* / hes family bHLH transcription factor 2*ENSMUSG0000002894023


Protein motifs (from Interpro)
Interpro ID Name
 IPR003650  Orange domain
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR036638  Helix-loop-helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IMP
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IMP
 biological_processGO:0030154 cell differentiation IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005667 transcription factor complex IDA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IDA
 molecular_functionGO:0003712 transcription coregulator activity IDA
 molecular_functionGO:0008134 transcription factor binding NAS
 molecular_functionGO:0042803 protein homodimerization activity ISO
 molecular_functionGO:0046982 protein heterodimerization activity ISO
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr