ENSMUSG00000067148


Mus musculus

Features
Gene ID: ENSMUSG00000067148
  
Biological name :Polr1c
  
Synonyms : DNA-directed RNA polymerases I and III subunit RPAC1 / P52432 / Polr1c
  
Possible biological names infered from orthology : O15160 / RNA polymerase I subunit C
  
Species: Mus musculus
  
Chr. number: 17
Strand: -1
Band: C
Gene start: 46243920
Gene end: 46248054
  
Corresponding Affymetrix probe sets: 10451238 (MoGene1.0st)   1417041_at (Mouse Genome 430 2.0 Array)   1449648_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000122026
Ensembl peptide - ENSMUSP00000133861
Ensembl peptide - ENSMUSP00000133597
Ensembl peptide - ENSMUSP00000084252
Ensembl peptide - ENSMUSP00000116998
NCBI entrez gene - 20016     See in Manteia.
MGI - MGI:103288
RefSeq - NM_009085
RefSeq Peptide - NP_033111
swissprot - G3UXX5
swissprot - D3Z7Q8
swissprot - P52432
swissprot - D3Z3D6
swissprot - G3UX92
Ensembl - ENSMUSG00000067148
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 polr1cENSDARG00000039400Danio rerio
 POLR1CENSGALG00000010349Gallus gallus
 O15160ENSG00000171453Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001514  DNA-directed RNA polymerase, 30-40kDa subunit, conserved site
 IPR011262  DNA-directed RNA polymerase, insert domain
 IPR011263  DNA-directed RNA polymerase, RpoA/D/Rpb3-type
 IPR033901  DNA-directed RNA polymerases I and III subunit AC40
 IPR036603  RNA polymerase, RBP11-like subunit
 IPR036643  DNA-directed RNA polymerase, insert domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000183 chromatin silencing at rDNA TAS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006360 transcription by RNA polymerase I IEA
 biological_processGO:0006366 transcription by RNA polymerase II TAS
 biological_processGO:0006383 transcription by RNA polymerase III IEA
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005666 DNA-directed RNA polymerase III complex IEA
 cellular_componentGO:0005736 DNA-directed RNA polymerase I complex IDA
 molecular_functionGO:0001054 RNA polymerase I activity IBA
 molecular_functionGO:0001056 RNA polymerase III activity IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003899 DNA-directed 5"-3" RNA polymerase activity IEA
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
B-WICH complex positively regulates rRNA expression
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase I Chain Elongation
RNA Polymerase I Transcription Termination
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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