ENSMUSG00000068536


Mus musculus

Features
Gene ID: ENSMUSG00000068536
  
Biological name :Doxl2
  
Synonyms : Doxl2
  
Possible biological names infered from orthology : amine oxidase, copper containing 1 / AOC1 / P19801
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: B2.3
Gene start: 48974963
Gene end: 48978746
  
Corresponding Affymetrix probe sets: 10538174 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000087517
Ensembl peptide - ENSMUSP00000139012
NCBI entrez gene - 243376     See in Manteia.
MGI - MGI:3618290
RefSeq - NM_001029987
RefSeq - XM_017321583
RefSeq Peptide - NP_001025158
swissprot - F6TPL1
swissprot - Q6IMK7
Ensembl - ENSMUSG00000068536
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 aoc1ENSDARG00000061355Danio rerio
 ENSGALG00000036190Gallus gallus
 AOC1ENSG00000002726Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Aoc1 / P19801* / amine oxidase, copper containing 1*ENSMUSG0000002981160
Svs1 / seminal vesicle secretory protein 1 / AOC1* / P19801* / amine oxidase, copper containing 1*ENSMUSG0000003921553
1600015I10Rik / RIKEN cDNA 1600015I10 gene / AOC1* / P19801* / amine oxidase, copper containing 1*ENSMUSG0000002981352
Aoc3 / O70423 / Membrane primary amine oxidase / Q16853* / amine oxidase, copper containing 3*ENSMUSG0000001932633
Aoc2 / Q812C9 / Retina-specific copper amine oxidase / O75106* / amine oxidase, copper containing 2*ENSMUSG0000007865132


Protein motifs (from Interpro)
Interpro ID Name
 IPR000269  Copper amine oxidase
 IPR015798  Copper amine oxidase, catalytic domain
 IPR015800  Copper amine oxidase, N2-terminal
 IPR015802  Copper amine oxidase, N3-terminal
 IPR016182  Copper amine oxidase, N-terminal
 IPR036460  Copper amine oxidase, catalytic domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 biological_processGO:0009308 amine metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005507 copper ion binding IEA
 molecular_functionGO:0008131 primary amine oxidase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0048038 quinone binding IEA


Pathways (from Reactome)
Pathway description
Phase I - Functionalization of compounds
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0009142 decreased prepulse inhibition "decrease in the ability of a relatively mild stimulus to suppress the response to a strong, startle-eliciting stimulus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Cecr2tm2b(EUCOMM)Hmgu/Cecr2+
Genetic Background: C57BL/6N-Cecr2tm2b(EUCOMM)Hmgu/Tcp

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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