ENSMUSG00000068739


Mus musculus

Features
Gene ID: ENSMUSG00000068739
  
Biological name :Sars
  
Synonyms : P26638 / Sars / Serine--tRNA ligase, cytoplasmic
  
Possible biological names infered from orthology : P49591 / seryl-tRNA synthetase
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: F3
Gene start: 108424865
Gene end: 108445209
  
Corresponding Affymetrix probe sets: 10501358 (MoGene1.0st)   1426257_a_at (Mouse Genome 430 2.0 Array)   1452000_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000118676
Ensembl peptide - ENSMUSP00000120879
Ensembl peptide - ENSMUSP00000088041
Ensembl peptide - ENSMUSP00000099685
NCBI entrez gene - 20226     See in Manteia.
MGI - MGI:102809
RefSeq - NM_001204979
RefSeq - NM_011319
RefSeq Peptide - NP_001191908
RefSeq Peptide - NP_035449
swissprot - Q8C483
swissprot - A2AFS0
swissprot - P26638
swissprot - A2AFS1
Ensembl - ENSMUSG00000068739
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sarsENSDARG00000008237Danio rerio
 SARSENSGALG00000026809Gallus gallus
 SARSENSG00000031698Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002314  Aminoacyl-tRNA synthetase, class II (G/ P/ S/T)
 IPR002317  Serine-tRNA ligase, type1
 IPR006195  Aminoacyl-tRNA synthetase, class II
 IPR010978  Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm
 IPR015866  Serine-tRNA synthetase, type1, N-terminal
 IPR033729  Serine-tRNA ligase catalytic core domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II ISS
 biological_processGO:0006412 translation IEA
 biological_processGO:0006418 tRNA aminoacylation for protein translation IEA
 biological_processGO:0006434 seryl-tRNA aminoacylation IEA
 biological_processGO:0016525 negative regulation of angiogenesis ISO
 biological_processGO:0097056 selenocysteinyl-tRNA(Sec) biosynthetic process IEA
 biological_processGO:1904046 negative regulation of vascular endothelial growth factor production ISO
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0001046 core promoter sequence-specific DNA binding ISO
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0004812 aminoacyl-tRNA ligase activity IEA
 molecular_functionGO:0004828 serine-tRNA ligase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016874 ligase activity IEA
 molecular_functionGO:0042803 protein homodimerization activity ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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