ENSMUSG00000069805


Mus musculus

Features
Gene ID: ENSMUSG00000069805
  
Biological name :Fbp1
  
Synonyms : Fbp1 / Fructose-1,6-bisphosphatase 1 / Q9QXD6
  
Possible biological names infered from orthology : fructose-bisphosphatase 1 / P09467
  
Species: Mus musculus
  
Chr. number: 13
Strand: -1
Band: B3
Gene start: 62864753
Gene end: 62888282
  
Corresponding Affymetrix probe sets: 10410007 (MoGene1.0st)   1448470_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000090564
Ensembl peptide - ENSMUSP00000115703
Ensembl peptide - ENSMUSP00000117146
NCBI entrez gene - 14121     See in Manteia.
MGI - MGI:95492
RefSeq - XM_011244488
RefSeq - NM_019395
RefSeq Peptide - NP_062268
swissprot - E9Q0T7
swissprot - Q9QXD6
swissprot - F6YS63
Ensembl - ENSMUSG00000069805
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FBP1ENSGALG00000012613Gallus gallus
 FBP1ENSG00000165140Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Fbp2 / P70695 / Fructose-1,6-bisphosphatase isozyme 2 / O00757* / fructose-bisphosphatase 2*ENSMUSG0000002145671


Protein motifs (from Interpro)
Interpro ID Name
 IPR000146  Fructose-1,6-bisphosphatase class 1
 IPR020548  Fructose-1,6-bisphosphatase, active site
 IPR028343  Fructose-1,6-bisphosphatase
 IPR033391  Fructose-1-6-bisphosphatase class I, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0005986 sucrose biosynthetic process IBA
 biological_processGO:0006000 fructose metabolic process IBA
 biological_processGO:0006002 fructose 6-phosphate metabolic process IEA
 biological_processGO:0006094 gluconeogenesis ISO
 biological_processGO:0006111 regulation of gluconeogenesis IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0030308 negative regulation of cell growth IEA
 biological_processGO:0030388 fructose 1,6-bisphosphate metabolic process IBA
 biological_processGO:0035690 cellular response to drug IEA
 biological_processGO:0045820 negative regulation of glycolytic process IEA
 biological_processGO:0046580 negative regulation of Ras protein signal transduction IEA
 biological_processGO:0051289 protein homotetramerization IEA
 biological_processGO:0071286 cellular response to magnesium ion IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol ISS
 molecular_functionGO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0016208 AMP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA
 molecular_functionGO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity ISO
 molecular_functionGO:0042578 phosphoric ester hydrolase activity IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0046872 metal ion binding ISO
 molecular_functionGO:0048029 monosaccharide binding ISS


Pathways (from Reactome)
Pathway description
Gluconeogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000069805 Fbp1 / Q9QXD6 / Fructose-1,6-bisphosphatase 1 / P09467* / fructose-bisphosphatase 1*  / complex






 

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