ENSMUSG00000071553


Mus musculus

Features
Gene ID: ENSMUSG00000071553
  
Biological name :Cpa2
  
Synonyms : Carboxypeptidase A2 / Cpa2 / Q504N0
  
Possible biological names infered from orthology : P48052
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: A3.3
Gene start: 30541582
Gene end: 30564476
  
Corresponding Affymetrix probe sets: 10537014 (MoGene1.0st)   1454623_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000093771
NCBI entrez gene - 232680     See in Manteia.
MGI - MGI:3617840
RefSeq - NM_001024698
RefSeq - XM_011241057
RefSeq Peptide - NP_001019869
swissprot - Q504N0
Ensembl - ENSMUSG00000071553
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cpa2ENSDARG00000010146Danio rerio
 cpa4ENSDARG00000043722Danio rerio
 CPA2ENSGALG00000008048Gallus gallus
 CPA2ENSG00000158516Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cpa4 / Q6P8K8 / Carboxypeptidase A4 / Q9UI42*ENSMUSG0000003907062
Cpa1 / Q7TPZ8 / Carboxypeptidase A1 / P15085*ENSMUSG0000005444660
Cpa5 / Q8R4H4 / Carboxypeptidase A5 / Q8WXQ8*ENSMUSG0000002978852
Cpb1 / carboxypeptidase B1 (tissue) / P15086* / carboxypeptidase B1*ENSMUSG0000001146342
Cpa6 / Q5U901 / Carboxypeptidase A6 / Q8N4T0*ENSMUSG0000004250138
Cpb2 / Q9JHH6 / Carboxypeptidase B2 / Q96IY4*ENSMUSG0000002199937
Cpa3 / P15089 / Mast cell carboxypeptidase A / P15088* / carboxypeptidase A3*ENSMUSG0000000186537


Protein motifs (from Interpro)
Interpro ID Name
 IPR000834  Peptidase M14, carboxypeptidase A
 IPR003146  Carboxypeptidase, activation peptide
 IPR034248  Carboxypeptidase A, carboxypeptidase domain
 IPR036990  Metallocarboxypeptidase-like, propeptide


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 cellular_componentGO:0005576 extracellular region ISO
 cellular_componentGO:0005615 extracellular space IBA
 molecular_functionGO:0004180 carboxypeptidase activity ISO
 molecular_functionGO:0004181 metallocarboxypeptidase activity ISO
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding ISO
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001926 female infertility "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193]
Show

Allelic Composition: Coq6tm1b(EUCOMM)Hmgu/Coq6tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Coq6tm1b(EUCOMM)Hmgu/J

 MP:0003020 decreased circulating chloride level "reduced concentration of chlorine salts in the circulation" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission]
Show

Allelic Composition: Coq6tm1b(EUCOMM)Hmgu/Coq6tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Coq6tm1b(EUCOMM)Hmgu/J

 MP:0005634 decreased circulating sodium level "less than the normal concentration in the blood of this metallic element, the most plentiful extracellular ion in the body and the principal determinant of extracellular fluid volume" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]
Show

Allelic Composition: Coq6tm1b(EUCOMM)Hmgu/Coq6tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Coq6tm1b(EUCOMM)Hmgu/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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