ENSMUSG00000074576


Mus musculus

Features
Gene ID: ENSMUSG00000074576
  
Biological name :Mocs3
  
Synonyms : A2BDX3 / Adenylyltransferase and sulfurtransferase MOCS3 Molybdopterin-synthase adenylyltransferase Molybdopterin-synthase sulfurtransferase / Mocs3
  
Possible biological names infered from orthology : molybdenum cofactor synthesis 3 / O95396
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: H3
Gene start: 168230622
Gene end: 168232594
  
Corresponding Affymetrix probe sets: 10478913 (MoGene1.0st)   1428924_at (Mouse Genome 430 2.0 Array)   1439242_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000096670
NCBI entrez gene - 69372     See in Manteia.
MGI - MGI:1916622
RefSeq - NM_001160330
RefSeq Peptide - NP_001153802
swissprot - A2BDX3
Ensembl - ENSMUSG00000074576
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mocs3ENSDARG00000008239Danio rerio
 MOCS3ENSGALG00000007986Gallus gallus
 MOCS3ENSG00000124217Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000594  THIF-type NAD/FAD binding fold
 IPR001763  Rhodanese-like domain
 IPR028885  Adenylyltransferase and sulfurtransferase MOCS3/Uba4
 IPR035985  Ubiquitin-activating enzyme
 IPR036873  Rhodanese-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002098 tRNA wobble uridine modification IEA
 biological_processGO:0002143 tRNA wobble position uridine thiolation IBA
 biological_processGO:0006777 Mo-molybdopterin cofactor biosynthetic process ISO
 biological_processGO:0008033 tRNA processing IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0018192 enzyme active site formation via cysteine modification to L-cysteine persulfide IEA
 biological_processGO:0032447 protein urmylation IBA
 biological_processGO:0034227 tRNA thio-modification IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol ISS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004792 thiosulfate sulfurtransferase activity ISO
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008641 ubiquitin-like modifier activating enzyme activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016779 nucleotidyltransferase activity IEA
 molecular_functionGO:0016783 sulfurtransferase activity IEA
 molecular_functionGO:0042292 URM1 activating enzyme activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061604 molybdopterin-synthase sulfurtransferase activity IEA
 molecular_functionGO:0061605 molybdopterin-synthase adenylyltransferase activity IEA


Pathways (from Reactome)
Pathway description
Molybdenum cofactor biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000027618 Nfs1 / Q9Z1J3 / Cysteine desulfurase, mitochondrial / Q9Y697* / AL109827.1* / NFS1, cysteine desulfurase*  / reaction






 

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