ENSMUSG00000078429


Mus musculus

Features
Gene ID: ENSMUSG00000078429
  
Biological name :Ctdsp2
  
Synonyms : Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 / Ctdsp2 / Q8BX07
  
Possible biological names infered from orthology : CTD small phosphatase 2 / O14595
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: D3
Gene start: 126978717
Gene end: 126999975
  
Corresponding Affymetrix probe sets: 10366767 (MoGene1.0st)   10367544 (MoGene1.0st)   1423660_at (Mouse Genome 430 2.0 Array)   1423661_s_at (Mouse Genome 430 2.0 Array)   1451075_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000100890
Ensembl peptide - ENSMUSP00000100891
NCBI entrez gene - 52468     See in Manteia.
MGI - MGI:1098748
RefSeq - XM_017314028
RefSeq - NM_001113470
RefSeq - NM_146012
RefSeq Peptide - NP_666124
RefSeq Peptide - NP_001106941
swissprot - Q8BX07
swissprot - Q8R3B3
Ensembl - ENSMUSG00000078429
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ctdsp2ENSDARG00000036102Danio rerio
 CTDSP2ENSG00000175215Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ctdspl / P58465 / CTD small phosphatase-like protein / O15194* / CTD small phosphatase like*ENSMUSG0000004740964
Ctdsp1 / P58466 / Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 / Q9GZU7* / CTD small phosphatase 1*ENSMUSG0000002617659
Q3TP92 / Ctdnep1 / CTD nuclear envelope phosphatase 1 / O95476*ENSMUSG0000001855930


Protein motifs (from Interpro)
Interpro ID Name
 IPR004274  FCP1 homology domain
 IPR011948  Dullard phosphatase domain, eukaryotic
 IPR023214  HAD superfamily
 IPR036412  HAD-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001933 negative regulation of protein phosphorylation IDA
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:2000134 negative regulation of G1/S transition of mitotic cell cycle IDA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IBA
 molecular_functionGO:0008420 CTD phosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000274 enlarged heart "increase over normal size of the heart" [J:29971]
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Allelic Composition: Cecr2tm2b(EUCOMM)Hmgu/Cecr2+
Genetic Background: C57BL/6N-Cecr2tm2b(EUCOMM)Hmgu/Tcp

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Clrn1tm1.1(KOMP)Vlcg/Clrn1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Clrn1tm1.1(KOMP)Vlcg/Ucd

 MP:0013294 prenatal lethality prior to heart atrial septation "death prior to the completion of heart atrial septation (Mus: E14.5-15.5)" [MGI:smb]
Show

Allelic Composition: Clrn1tm1.1(KOMP)Vlcg/Clrn1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Clrn1tm1.1(KOMP)Vlcg/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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