ENSMUSG00000078619


Mus musculus

Features
Gene ID: ENSMUSG00000078619
  
Biological name :Smarcd2
  
Synonyms : Q99JR8 / Smarcd2 / SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2
  
Possible biological names infered from orthology : Q92925
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: E1
Gene start: 106263179
Gene end: 106272972
  
Corresponding Affymetrix probe sets: 10392120 (MoGene1.0st)   1426192_at (Mouse Genome 430 2.0 Array)   1448400_a_at (Mouse Genome 430 2.0 Array)   1448401_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000021052
Ensembl peptide - ENSMUSP00000102456
Ensembl peptide - ENSMUSP00000133629
NCBI entrez gene - 83796     See in Manteia.
MGI - MGI:1933621
RefSeq - XM_006534552
RefSeq - NM_001130187
RefSeq - NM_031878
RefSeq Peptide - NP_001123659
RefSeq Peptide - NP_114084
swissprot - Q99JR8
swissprot - G3UXC0
Ensembl - ENSMUSG00000078619
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 smarcd2ENSDARG00000088877Danio rerio
 SMARCD2ENSGALG00000029304Gallus gallus
 Q92925ENSG00000108604Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q6P9Z1 / Smarcd3 / SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 / Q6STE5*ENSMUSG0000002894962
Q61466 / Smarcd1 / SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 / Q96GM5*ENSMUSG0000002301861


Protein motifs (from Interpro)
Interpro ID Name
 IPR003121  SWIB/MDM2 domain
 IPR019835  SWIB domain
 IPR030090  SWI/SNF complex subunit BAF60B
 IPR036885  SWIB/MDM2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006337 nucleosome disassembly IEA
 biological_processGO:0006338 chromatin remodeling IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0043044 ATP-dependent chromatin remodeling IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0016514 SWI/SNF complex IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
RMTs methylate histone arginines
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001697 abnormal embryo size "anomalous proportions of embryo compared to littermates" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
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Allelic Composition: Pip5k1ctm1a(KOMP)Wtsi/Pip5k1ctm1a(KOMP)Wtsi
Genetic Background: C57BL/6N-Pip5k1ctm1a(KOMP)Wtsi/Wtsi

 MP:0002092 abnormal eye morphology "abnormal development of the eye tissues resulting in morphological abnormality or abnormal structure of the visual system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Pip5k1ctm1a(KOMP)Wtsi/Pip5k1ctm1a(KOMP)Wtsi
Genetic Background: C57BL/6N-Pip5k1ctm1a(KOMP)Wtsi/Wtsi

 MP:0002192 hydrops fetalis "an abnormal accumulation of serous fluid in fetal tissues" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Ralatm1a(EUCOMM)Wtsi/Ralatm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Ralatm1a(EUCOMM)Wtsi/Wtsi

Allelic Composition: Smarcd2tm1.1(KOMP)Vlcg/Smarcd2+
Genetic Background: C57BL/6N-Smarcd2tm1.1(KOMP)Vlcg/Ucd

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Ralatm1a(EUCOMM)Wtsi/Ralatm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Ralatm1a(EUCOMM)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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