ENSMUSG00000090112


Mus musculus

Features
Gene ID: ENSMUSG00000090112
  
Biological name :Shprh
  
Synonyms : E3 ubiquitin-protein ligase SHPRH / Q7TPQ3 / Shprh
  
Possible biological names infered from orthology : Q149N8 / SNF2 histone linker PHD RING helicase
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: A1
Gene start: 11149427
Gene end: 11217595
  
Corresponding Affymetrix probe sets: 10361712 (MoGene1.0st)   1430582_at (Mouse Genome 430 2.0 Array)   1440994_at (Mouse Genome 430 2.0 Array)   1452261_at (Mouse Genome 430 2.0 Array)   1457327_at (Mouse Genome 430 2.0 Array)   1458594_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000125457
Ensembl peptide - ENSMUSP00000039422
Ensembl peptide - ENSMUSP00000125127
Ensembl peptide - ENSMUSP00000125849
Ensembl peptide - ENSMUSP00000132870
NCBI entrez gene - 268281     See in Manteia.
MGI - MGI:1917581
RefSeq - XM_006512740
RefSeq - NM_001077707
RefSeq - NM_001284354
RefSeq - NM_172937
RefSeq Peptide - NP_001071175
RefSeq Peptide - NP_001271283
RefSeq Peptide - NP_766525
swissprot - Q7TPQ3
swissprot - F7D4T4
Ensembl - ENSMUSG00000090112
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 shprhENSDARG00000075884Danio rerio
 SHPRHENSGALG00000012289Gallus gallus
 SHPRHENSG00000146414Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000330  SNF2-related, N-terminal domain
 IPR001650  Helicase, C-terminal
 IPR001841  Zinc finger, RING-type
 IPR001965  Zinc finger, PHD-type
 IPR005818  Linker histone H1/H5, domain H15
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR019786  Zinc finger, PHD-type, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination ISO
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006334 nucleosome assembly IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus ISO
 biological_processGO:0016567 protein ubiquitination IEA
 cellular_componentGO:0000786 nucleosome IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity ISO
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding ISO
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000022674 Q9D2M8 / Ube2v2 / ubiquitin-conjugating enzyme E2 variant 2 / Q15819* / ubiquitin conjugating enzyme E2 V2*  / complex
 ENSMUSG00000020390 Ube2b / P63147 / ubiquitin-conjugating enzyme E2B / P63146*  / complex
 ENSMUSG00000030254 Rad18 / Q9QXK2 / RAD18 E3 ubiquitin protein ligase / Q9NS91*  / complex
 ENSMUSG00000027342 Pcna / P17918 / proliferating cell nuclear antigen / P12004*  / complex






 

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