ENSMUSG00000092558


Mus musculus

Features
Gene ID: ENSMUSG00000092558
  
Biological name :Med20
  
Synonyms : Med20 / Mediator of RNA polymerase II transcription subunit 20 / Q9R0X0
  
Possible biological names infered from orthology : mediator complex subunit 20 / Q9H944
  
Species: Mus musculus
  
Chr. number: 17
Strand: 1
Band: C
Gene start: 47611582
Gene end: 47624418
  
Corresponding Affymetrix probe sets: 10445695 (MoGene1.0st)   1416826_a_at (Mouse Genome 430 2.0 Array)   1448478_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000024778
NCBI entrez gene - 56771     See in Manteia.
MGI - MGI:1929648
RefSeq - NM_020048
RefSeq Peptide - NP_064432
swissprot - Q9R0X0
Ensembl - ENSMUSG00000092558
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 med20ENSDARG00000046006Danio rerio
 MED20ENSGALG00000003474Gallus gallus
 MED20ENSG00000124641Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gm20517ENSMUSG0000002398467


Protein motifs (from Interpro)
Interpro ID Name
 IPR013921  Mediator complex, subunit Med20


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0035914 skeletal muscle cell differentiation IMP
 cellular_componentGO:0000151 ubiquitin ligase complex IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0016592 mediator complex IDA
 molecular_functionGO:0003713 transcription coactivator activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0061630 ubiquitin protein ligase activity IEA


Pathways (from Reactome)
Pathway description
Generic Transcription Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000221 decreased WBC count "fewer than normal numbers of WBCs" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Kiss1rtm1.1(KOMP)Vlcg/Kiss1rtm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Kiss1rtm1.1(KOMP)Vlcg/Ucd

 MP:0001364 decreased anxiety-related response "when compared to controls, subjects exhibit fewer responses thought to be indicative of anxiety in behavioral tests" [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator, J:86626, J:85438, J:64043]
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Allelic Composition: Kiss1rtm1.1(KOMP)Vlcg/Kiss1rtm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Kiss1rtm1.1(KOMP)Vlcg/Ucd

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Kiss1rtm1.1(KOMP)Vlcg/Kiss1rtm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Kiss1rtm1.1(KOMP)Vlcg/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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