ENSDARG00000000563


Danio rerio

Features
Gene ID: ENSDARG00000000563
  
Biological name :ttn.1
  
Synonyms : titin, tandem duplicate 1 / ttn.1
  
Possible biological names infered from orthology : A2ASS6 / Q8WZ42 / titin / TTN
  
Species: Danio rerio
  
Chr. number: 9
Strand: -1
Band:
Gene start: 42732992
Gene end: 42873700
  
Corresponding Affymetrix probe sets: Dr.1662.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000107866
Ensembl peptide - ENSDARP00000145605
Ensembl peptide - ENSDARP00000157573
swissprot - G1K2X0
ZFIN ID - ZDB-GENE-030616-413
Ensembl - ENSDARG00000000563
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TTNENSG00000155657Homo sapiens
 TtnENSMUSG00000051747Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ttn.2 / titin, tandem duplicate 2 / TTN* / titin* / A2ASS6* / Q8WZ42*ENSDARG0000002821359
hmcn1 / hemicentin 1 / D3YXG0* / Q96RW7*ENSDARG000000169363
hmcn2 / hemicentin 2 / A2AJ76* / Q8NDA2*ENSDARG000000793272
obsl1a / obscurin-like 1a / OBSL1* / O75147* / obscurin like 1*ENSDARG000000036841
obscnb / obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF b / OBSCN* / Q5VST9* / obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF*ENSDARG000000221011
palld / palladin, cytoskeletal associated protein / Q8WX93* / Q9ET54* / Palladin *ENSDARG000000400091
mxra5a / matrix-remodelling associated 5a / MXRA5* / Q9NR99* / matrix remodeling associated 5*ENSDARG000000748151
mxra5b / matrix-remodelling associated 5b / MXRA5* / Q9NR99* / matrix remodeling associated 5*ENSDARG000000763091
si:ch211-159i8.4ENSDARG000000763321
obsl1b / obscurin-like 1b / OBSL1* / D3YYU8* / O75147* / obscurin like 1* / Obscurin-like protein 1 *ENSDARG000000773881
igsf10 / immunoglobulin superfamily, member 10 / Q3V1M1* / Q6WRI0*ENSDARG000000774971
CU928131.1ENSDARG000001092621
myot / myotilinENSDARG000000763120
hmcn2 / hemicentin 2ENSDARG000000860600


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR003961  Fibronectin type III
 IPR007110  Immunoglobulin-like domain
 IPR008266  Tyrosine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007519 skeletal muscle tissue development IGI
 biological_processGO:0014866 skeletal myofibril assembly IMP
 biological_processGO:0030239 myofibril assembly IGI
 biological_processGO:0048769 sarcomerogenesis IMP
 biological_processGO:0071688 striated muscle myosin thick filament assembly IGI
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Platelet degranulation
Striated Muscle Contraction


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000037 anatomical structure anatomical structure increased amount , abnormal
anatomical structure decreased amount , abnormal
anatomical structure amount , ameliorated
Show

 ZFA:0000076 swim bladder swim bladder uninflated , abnormal
Show

 ZFA:0000114 heart heart edematous , abnormal
Show

 ZFA:0000155 somite somite skeletal muscle cell disorganized , abnormal
somite myofibril disorganized , abnormal
somite sarcomere disorganized , abnormal
somite Z disc disorganized , abnormal
somite sarcomere spatial pattern , abnormal
somite Z disc spatial pattern , abnormal
Show

 ZFA:0000851 somite 12 somite 12 sarcomere decreased length , abnormal
somite 12 myosin filament decreased length , abnormal
somite 12 myosin filament disorganized , abnormal
Show

 ZFA:0000852 somite 15 somite 15 myosin filament disorganized , abnormal
Show

 ZFA:0000982 somite 6 somite 6 sarcomere decreased length , abnormal
somite 6 Z disc decreased width , abnormal
somite 6 myosin filament decreased length , abnormal
somite 6 myosin filament decreased width , abnormal
Show

 ZFA:0001056 myotome myotome sarcomere spatial pattern , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased size , abnormal
whole organism decreased behavioural activity , abnormal
whole organism decreased life span , abnormal
Show

 ZFA:0005277 skeletal muscle skeletal muscle sarcomere disorganized , abnormal
Show

 ZFA:0009115 skeletal muscle cell skeletal muscle cell nucleus shape , abnormal
skeletal muscle cell myofibril disorganized , abnormal
skeletal muscle cell Z disc disorganized , abnormal
skeletal muscle cell A band disorganized , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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