ENSDARG00000001939


Danio rerio

Features
Gene ID: ENSDARG00000001939
  
Biological name :b3gat3
  
Synonyms : b3gat3 / beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
  
Possible biological names infered from orthology : beta-1,3-glucuronyltransferase 3 / Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 / O94766 / P58158
  
Species: Danio rerio
  
Chr. number: 7
Strand: 1
Band:
Gene start: 25015151
Gene end: 25029261
  
Corresponding Affymetrix probe sets: Dr.20983.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000124815
Ensembl peptide - ENSDARP00000143934
NCBI entrez gene - 192334     See in Manteia.
swissprot - A0A286Y9T9
swissprot - F8W289
ZFIN ID - ZDB-GENE-020419-3
Ensembl - ENSDARG00000001939
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 B3GAT3ENSG00000149541Homo sapiens
 B3gat3ENSMUSG00000071649Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
b3gat2 / beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S) / P59270* / Q9NPZ5* / beta-1,3-glucuronyltransferase 2* / Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2 *ENSDARG0000003073345
b3gat1a / beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) a / Q9P2W7* / Q9CW73* / B3GAT1* / beta-1,3-glucuronyltransferase 1* / Galactosylgalactosylxylosylprotein 3-beta-glucur...ENSDARG0000004054743
CU633908.1ENSDARG0000011392842


Protein motifs (from Interpro)
Interpro ID Name
 IPR005027  Glycosyl transferase, family 43
 IPR029044  Nucleotide-diphospho-sugar transferases


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006486 protein glycosylation IEA
 biological_processGO:0015012 heparan sulfate proteoglycan biosynthetic process IMP
 biological_processGO:0030166 proteoglycan biosynthetic process IMP
 biological_processGO:0030198 extracellular matrix organization IMP
 biological_processGO:0050650 chondroitin sulfate proteoglycan biosynthetic process IMP
 biological_processGO:0051216 cartilage development IMP
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
A tetrasaccharide linker sequence is required for GAG synthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000095 pharyngeal arch 3-7 skeleton pharyngeal arch 3-7 skeleton quality , abnormal
Show

 ZFA:0000184 cleithrum cleithrum decreased size , abnormal
cleithrum malformed , abnormal
Show

 ZFA:0000250 opercle opercle decreased size , abnormal
opercle malformed , abnormal
Show

 ZFA:0001094 whole organism whole organism anterior-posterior axis dwarf-like , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
head cuboid , abnormal
Show

 ZFA:0001205 Meckel s cartilage Meckels cartilage structure , abnormal
Meckels cartilage chondrocyte disorganized , abnormal
Show

 ZFA:0001227 mandibular arch skeleton mandibular arch skeleton condensed , abnormal
mandibular arch skeleton shape , abnormal
mandibular arch skeleton morphology , abnormal
mandibular arch skeleton decreased length , abnormal
Show

 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage structure , abnormal
ceratohyal cartilage chondrocyte disorganized , abnormal
Show

 ZFA:0001458 cranial cartilage cranial cartilage morphology , abnormal
cranial cartilage deformed , abnormal
cranial cartilage collagen trimer morphology , abnormal
cranial cartilage collagen type I trimer decreased amount , abnormal
cranial cartilage collagen type II trimer decreased amount , abnormal
cranial cartilage collagen type VI trimer absent , abnormal
cranial cartilage extracellular matrix composition , abnormal
Show

 ZFA:0001460 pharyngeal arch cartilage pharyngeal arch cartilage decreased length , abnormal
pharyngeal arch cartilage increased thickness , abnormal
pharyngeal arch cartilage oriented , abnormal
pharyngeal arch cartilage chondrocyte circular , abnormal
pharyngeal arch cartilage chondrocyte disorganized , abnormal
Show

 ZFA:0001613 pharyngeal arch 3-7 pharyngeal arch 3-7 shape , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000001939 b3gat3 / beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I) / O94766* / P58158* / beta-1,3-glucuronyltransferase 3* / Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 *  / complex






 

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