ENSDARG00000002760


Danio rerio

Features
Gene ID: ENSDARG00000002760
  
Biological name :gdf5
  
Synonyms : gdf5 / growth differentiation factor 5
  
Possible biological names infered from orthology : P43026 / P43027
  
Species: Danio rerio
  
Chr. number: 6
Strand: -1
Band:
Gene start: 52637308
Gene end: 52661824
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000003126
Ensembl peptide - ENSDARP00000124399
NCBI entrez gene - 100334210     See in Manteia.
swissprot - F1QK08
swissprot - F8W3E7
ZFIN ID - ZDB-GENE-990415-39
Ensembl - ENSDARG00000002760
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GDF5ENSGALG00000038355Gallus gallus
 GDF5ENSG00000125965Homo sapiens
 Gdf5ENSMUSG00000038259Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gdf6a / P85857 / growth differentiation factor 6a / GDF6* / P43028* / Q6KF10* / growth differentiation factor 6*ENSDARG0000005347938
gdf6b / A8E7N9 / growth differentiation factor 6b / GDF6* / Q6KF10* / P43028* / growth differentiation factor 6*ENSDARG0000000551035
gdf7 / growth differentiation factor 7 / P43029* / Q7Z4P5*ENSDARG0000004278435
bmp4 / bone morphogenetic protein 4 / P12644* / P21275* / Bone morphotic protein 4 *ENSDARG0000001999523
bmp2b / bone morphogenetic protein 2b / BMP2* / P21274* / P12643* / Bone morphotic protein 2 * / bone morphogenetic protein 2*ENSDARG0000004143023
bmp2a / bone morphogenetic protein 2a / BMP2* / P21274* / P12643* / Bone morphotic protein 2 * / bone morphogenetic protein 2*ENSDARG0000001340922
bmp6 / bone morphogenetic protein 6 / P20722* / P22004* / Bone morphotic protein 6 *ENSDARG0000001568622
bmp7b / bone morphogenetic protein 7bENSDARG0000006323022
bmp7a / bone morphogenetic protein 7a / BMP7* / P23359* / P18075* / Bone morphotic protein 7 * / bone morphogenetic protein 7*ENSDARG0000001826021
admp / anti-dorsalizing morphogenic proteinENSDARG0000002537221
bmp10 / bone morphogenetic protein 10 / O95393* / Q9R229* / Bone morphotic protein 10 *ENSDARG0000006176921
bmp5 / bone morphogenetic protein 5 / P22003*ENSDARG0000010170121
bmp10l / bone morphogenetic protein 10, like / BMP10* / O95393* / bone morphogenetic protein 10*ENSDARG0000010923321
bmp16 / bone morphogenetic protein 16ENSDARG0000010367920
bmp8a / bone morphogenetic protein 8a / BMP8B* / Q7Z5Y6* / P34820* / P34821* / P55105* / Bone morphotic protein 8B * / Bone morphotic protein 8A * / bone morphogenetic protein 8b*ENSDARG0000003567718
gdf2 / F1QWZ4 / growth differentiation factor 2 / Q9UK05* / Q9WV56*ENSDARG0000005917318


Protein motifs (from Interpro)
Interpro ID Name
 IPR001111  TGF-beta, propeptide
 IPR001839  Transforming growth factor-beta, C-terminal
 IPR015615  Transforming growth factor-beta-related
 IPR017948  Transforming growth factor beta, conserved site
 IPR029034  Cystine-knot cytokine


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation IBA
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0043408 regulation of MAPK cascade IBA
 biological_processGO:0048468 cell development IBA
 biological_processGO:0060395 SMAD protein signal transduction IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IBA
 molecular_functionGO:0005125 cytokine activity IBA
 molecular_functionGO:0005160 transforming growth factor beta receptor binding IBA
 molecular_functionGO:0008083 growth factor activity IEA


Pathways (from Reactome)
Pathway description
Molecules associated with elastic fibres


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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