ENSGALG00000038355


Gallus gallus

Features
Gene ID: ENSGALG00000038355
  
Biological name :GDF5
  
Synonyms : GDF5 / growth/differentiation factor 5 precursor
  
Possible biological names infered from orthology : growth differentiation factor 5 / P43026 / P43027
  
Species: Gallus gallus
  
Chr. number: 20
Strand: 1
Band:
Gene start: 1257698
Gene end: 1260753
  
Corresponding Affymetrix probe sets: Gga.3403.1.S1_at (Chicken Array)   Gga.3403.1.S2_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000051988
NCBI entrez gene - 374249     See in Manteia.
RefSeq - NM_204338
RefSeq Peptide - NP_989669
swissprot - A0A1D5PGR5
Ensembl - ENSGALG00000038355
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gdf5ENSDARG00000002760Danio rerio
 GDF5ENSG00000125965Homo sapiens
 Gdf5ENSMUSG00000038259Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GDF6 / growth differentiation factor 6 / P43028* / Q6KF10*ENSGALG0000003590131
BMP8B* / BMP8A* / Q7Z5Y6* / P34820* / P34821* / P55105* / Bone morphotic protein 8A * / Bone morphotic protein 8B * / bone morphogenetic protein 8a* / bone morphogenetic protein 8b*ENSGALG0000003898423
BMP10 / bone morphogenetic protein 10 / O95393* / Q9R229* / Bone morphotic protein 10 *ENSGALG0000000012022
BMP4 / bone morphogenetic protein 4 / P12644* / P21275* / Bone morphotic protein 4 *ENSGALG0000001242922
BMP2 / bone morphogenetic protein 2 precursor / P12643* / P21274* / Bone morphotic protein 2 * / bone morphogenetic protein 2*ENSGALG0000002930122
BMP7 / bone morphogenetic protein 7 / P18075* / P23359* / Bone morphotic protein 7 *ENSGALG0000000766821
BMP5 / bone morphogenetic protein 5 / P22003* / P49003* / Bone morphotic protein 5 *ENSGALG0000001629321
GDF2 / P34822 / Dorsalin-1 / Q9WV56* / Q9UK05* / growth differentiation factor 2*ENSGALG0000000598120
BMP6 / bone morphogenetic protein 6 / P20722* / P22004* / Bone morphotic protein 6 *ENSGALG0000001278719
ADMP / anti-dorsalizing morphogenetic protein precursor ENSGALG0000003740819
ENSGALG0000000623915


Protein motifs (from Interpro)
Interpro ID Name
 IPR001111  TGF-beta, propeptide
 IPR001839  Transforming growth factor-beta, C-terminal
 IPR015615  Transforming growth factor-beta-related
 IPR017948  Transforming growth factor beta, conserved site
 IPR029034  Cystine-knot cytokine


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002062 chondrocyte differentiation IEA
 biological_processGO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0030326 embryonic limb morphogenesis IEA
 biological_processGO:0030513 positive regulation of BMP signaling pathway IEA
 biological_processGO:0032331 negative regulation of chondrocyte differentiation IEA
 biological_processGO:0032332 positive regulation of chondrocyte differentiation IEA
 biological_processGO:0035136 forelimb morphogenesis IEA
 biological_processGO:0035137 hindlimb morphogenesis IEA
 biological_processGO:0040014 regulation of multicellular organism growth IEA
 biological_processGO:0050680 negative regulation of epithelial cell proliferation IEA
 biological_processGO:0060395 SMAD protein signal transduction IEA
 biological_processGO:0060591 chondroblast differentiation IEA
 biological_processGO:2001054 negative regulation of mesenchymal cell apoptotic process IEA
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0008083 growth factor activity IEA
 molecular_functionGO:0036122 BMP binding IEA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
Molecules associated with elastic fibres


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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