ENSGALG00000012787


Gallus gallus

Features
Gene ID: ENSGALG00000012787
  
Biological name :BMP6
  
Synonyms : BMP6 / bone morphogenetic protein 6
  
Possible biological names infered from orthology : Bone morphotic protein 6 / P20722 / P22004
  
Species: Gallus gallus
  
Chr. number: 2
Strand: -1
Band:
Gene start: 64587752
Gene end: 64609767
  
Corresponding Affymetrix probe sets: GgaAffx.23995.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000020833
NCBI entrez gene - 420868     See in Manteia.
RefSeq - XM_015275997
swissprot - F1P4H2
Ensembl - ENSGALG00000012787
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 bmp6ENSDARG00000015686Danio rerio
 BMP6ENSG00000153162Homo sapiens
 Bmp6ENSMUSG00000039004Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BMP5 / bone morphogenetic protein 5 / P22003* / P49003* / Bone morphotic protein 5 *ENSGALG0000001629366
BMP7 / bone morphogenetic protein 7 / P18075* / P23359* / Bone morphotic protein 7 *ENSGALG0000000766865
BMP8B* / BMP8A* / Q7Z5Y6* / P34820* / P34821* / P55105* / Bone morphotic protein 8A * / Bone morphotic protein 8B * / bone morphogenetic protein 8a* / bone morphogenetic protein 8b*ENSGALG0000003898451
BMP4 / bone morphogenetic protein 4 / P12644* / P21275* / Bone morphotic protein 4 *ENSGALG0000001242935
BMP2 / bone morphogenetic protein 2 precursor / P12643* / P21274* / Bone morphotic protein 2 * / bone morphogenetic protein 2*ENSGALG0000002930135
GDF5 / growth/differentiation factor 5 precursor / P43026* / P43027* / growth differentiation factor 5*ENSGALG0000003835530
GDF2 / P34822 / Dorsalin-1 / Q9WV56* / Q9UK05* / growth differentiation factor 2*ENSGALG0000000598129
BMP10 / bone morphogenetic protein 10 / O95393* / Q9R229* / Bone morphotic protein 10 *ENSGALG0000000012028
ENSGALG0000000623928
ADMP / anti-dorsalizing morphogenetic protein precursor ENSGALG0000003740827
GDF6 / growth differentiation factor 6 / P43028* / Q6KF10*ENSGALG0000003590122


Protein motifs (from Interpro)
Interpro ID Name
 IPR001111  TGF-beta, propeptide
 IPR001839  Transforming growth factor-beta, C-terminal
 IPR015615  Transforming growth factor-beta-related
 IPR017948  Transforming growth factor beta, conserved site
 IPR029034  Cystine-knot cytokine


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001649 osteoblast differentiation IEA
 biological_processGO:0001654 eye development IEA
 biological_processGO:0001822 kidney development IEA
 biological_processGO:0001938 positive regulation of endothelial cell proliferation IEA
 biological_processGO:0001958 endochondral ossification IEA
 biological_processGO:0003323 type B pancreatic cell development IEA
 biological_processGO:0006879 cellular iron ion homeostasis IEA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0006955 immune response IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030501 positive regulation of bone mineralization IEA
 biological_processGO:0030509 BMP signaling pathway IEA
 biological_processGO:0030539 male genitalia development IEA
 biological_processGO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway IEA
 biological_processGO:0032349 positive regulation of aldosterone biosynthetic process IEA
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0043408 regulation of MAPK cascade IBA
 biological_processGO:0045603 positive regulation of endothelial cell differentiation IEA
 biological_processGO:0045666 positive regulation of neuron differentiation IEA
 biological_processGO:0045669 positive regulation of osteoblast differentiation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048468 cell development IBA
 biological_processGO:0050679 positive regulation of epithelial cell proliferation IEA
 biological_processGO:0060391 positive regulation of SMAD protein signal transduction IEA
 biological_processGO:0060395 SMAD protein signal transduction IEA
 biological_processGO:0060586 multicellular organismal iron ion homeostasis IEA
 biological_processGO:0071281 cellular response to iron ion IEA
 biological_processGO:0071773 cellular response to BMP stimulus IEA
 biological_processGO:2000872 positive regulation of progesterone secretion TAS
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005623 cell IEA
 molecular_functionGO:0005125 cytokine activity IBA
 molecular_functionGO:0005160 transforming growth factor beta receptor binding IBA
 molecular_functionGO:0008083 growth factor activity IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0070700 BMP receptor binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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