ENSDARG00000006640


Danio rerio

Features
Gene ID: ENSDARG00000006640
  
Biological name :eomesa
  
Synonyms : eomesa / eomesodermin homolog a
  
Possible biological names infered from orthology : EOMES / eomesodermin / Eomesodermin homolog / O54839 / O95936
  
Species: Danio rerio
  
Chr. number: 19
Strand: -1
Band:
Gene start: 860830
Gene end: 874888
  
Corresponding Affymetrix probe sets: Dr.10724.1.S1_at (Zebrafish Array)   NM_131679_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000007733
Ensembl peptide - ENSDARP00000111994
Ensembl peptide - ENSDARP00000146371
NCBI entrez gene - 64603     See in Manteia.
RefSeq - NM_131679
RefSeq - XM_005159321
RefSeq Peptide - NP_571754
swissprot - Q98TU2
ZFIN ID - ZDB-GENE-001228-1
Ensembl - ENSDARG00000006640
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EOMESENSGALG00000027247Gallus gallus
 EOMESENSG00000163508Homo sapiens
 EomesENSMUSG00000032446Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
eomesb / eomesodermin homolog b / EOMES* / O95936* / eomesodermin*ENSDARG0000010424352
tbr1b / T-box, brain, 1b / TBR1* / Q16650* / T-box, brain 1*ENSDARG0000000471247
tbx21 / T-box 21 / Q9JKD8* / Q9UL17* / T-box transcription factor TBX21 *ENSDARG0000000447339
tbr1a / T-box, brain, 1aENSDARG0000007625938
mgaa / MGA, MAX dimerization protein a / MGA* / Q8IWI9* / A2AWL7* / MAX-associated protein * / MGA, MAX dimerization protein*ENSDARG0000007878420
tbxtb / T-box transcription factor Tb / T* / TBXT* / P20293* / O15178* / T-box transcription factor T* / brachyury, T-box transcription factor T*ENSDARG0000003980619
tbx19 / T-box 19 / O60806* / Q99ME7* / T-box transcription factor TBX19 *ENSDARG0000007918718
tbxta / Q07998 / T-box transcription factor TaENSDARG0000010157617
tbx6l / T-box 6, likeENSDARG0000000693915


Protein motifs (from Interpro)
Interpro ID Name
 IPR001699  Transcription factor, T-box
 IPR008967  p53-like transcription factor, DNA-binding
 IPR018186  Transcription factor, T-box, conserved site
 IPR032385  T-box transcription factor-associated


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001706 endoderm formation IMP
 biological_processGO:0001714 endodermal cell fate specification IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IMP
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0042074 cell migration involved in gastrulation IMP
 biological_processGO:0048263 determination of dorsal identity IMP
 biological_processGO:0048382 mesendoderm development IGI
 biological_processGO:0055109 invagination involved in gastrulation with mouth forming second IMP
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IDA
 molecular_functionGO:0003677 DNA binding IDA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000023 forerunner cell group forerunner cell group split , abnormal
Show

 ZFA:0000084 yolk yolk elongated , abnormal
yolk flattened , abnormal
yolk microtubule spatial pattern , abnormal
Show

 ZFA:0000088 YSL YSL nucleus aggregated , abnormal
YSL nucleus morphology , abnormal
Show

 ZFA:0000106 extension extension distended , abnormal
Show

 ZFA:0001173 dorsal fin dorsal fin absent , abnormal
Show

 ZFA:0001175 blastodisc blastodisc deep blastomere shape , abnormal
blastodisc deep blastomere crowded , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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