ENSDARG00000078784


Danio rerio

Features
Gene ID: ENSDARG00000078784
  
Biological name :mgaa
  
Synonyms : mgaa / MGA, MAX dimerization protein a
  
Possible biological names infered from orthology : A2AWL7 / MAX-associated protein / MGA / MGA, MAX dimerization protein / Q8IWI9
  
Species: Danio rerio
  
Chr. number: 17
Strand: 1
Band:
Gene start: 10566490
Gene end: 10590378
  
Corresponding Affymetrix probe sets: Dr.22484.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000126412
Ensembl peptide - ENSDARP00000145285
Ensembl peptide - ENSDARP00000144420
Ensembl peptide - ENSDARP00000136787
Ensembl peptide - ENSDARP00000099539
Ensembl peptide - ENSDARP00000115875
Ensembl peptide - ENSDARP00000122330
NCBI entrez gene - 569620     See in Manteia.
swissprot - E9QJ48
swissprot - A0A286YBQ8
swissprot - A0A0R4IQK3
swissprot - F1Q5T5
swissprot - F1R7N7
swissprot - K7DY84
ZFIN ID - ZDB-GENE-030603-1
Ensembl - ENSDARG00000078784
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000008653Gallus gallus
 ENSGALG00000031456Gallus gallus
 MGAENSG00000174197Homo sapiens
 MgaENSMUSG00000033943Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
tbr1b / T-box, brain, 1b / TBR1* / Q16650* / T-box, brain 1*ENSDARG000000047125
eomesa / eomesodermin homolog a / EOMES* / O95936* / eomesodermin*ENSDARG000000066405
tbx6l / T-box 6, likeENSDARG000000069395
tbx21 / T-box 21 / Q9JKD8* / Q9UL17* / T-box transcription factor TBX21 *ENSDARG000000044734
tbxtb / T-box transcription factor Tb / T* / TBXT* / P20293* / O15178* / T-box transcription factor T* / brachyury, T-box transcription factor T*ENSDARG000000398064
tbr1a / T-box, brain, 1aENSDARG000000762594
tbx19 / T-box 19 / O60806* / Q99ME7* / T-box transcription factor TBX19 *ENSDARG000000791874
tbxta / Q07998 / T-box transcription factor TaENSDARG000001015764
eomesb / eomesodermin homolog b / EOMES* / O95936* / eomesodermin*ENSDARG000001042434


Protein motifs (from Interpro)
Interpro ID Name
 IPR001699  Transcription factor, T-box
 IPR008967  p53-like transcription factor, DNA-binding
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR018186  Transcription factor, T-box, conserved site
 IPR032060  Domain of unknown function DUF4801


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001889 liver development IMP
 biological_processGO:0001947 heart looping IGI
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0030513 positive regulation of BMP signaling pathway IMP
 biological_processGO:0031016 pancreas development IMP
 biological_processGO:0048264 determination of ventral identity IMP
 biological_processGO:0048565 digestive tract development IMP
 biological_processGO:0048854 brain morphogenesis IMP
 biological_processGO:0070206 protein trimerization IPI
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0071141 SMAD protein complex IPI
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IDA
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
Transcriptional Regulation by E2F6


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000006 ball ball size , abnormal
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 ZFA:0000007 blood blood nucleate erythrocyte decreased amount , abnormal
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 ZFA:0000008 brain brain apoptotic , abnormal
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 ZFA:0000029 hindbrain hindbrain apoptotic , abnormal
hindbrain edematous , abnormal
hindbrain aplastic , abnormal
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 ZFA:0000042 midbrain hindbrain boundary midbrain hindbrain boundary amorphous , abnormal
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 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000106 extension extension degenerate , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000123 liver liver aplastic , abnormal
liver hypoplastic , abnormal
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 ZFA:0000128 midbrain midbrain apoptotic , abnormal
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 ZFA:0000140 pancreas pancreas aplastic , abnormal
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 ZFA:0000360 heart tube heart tube decreased thickness , abnormal
heart tube collapsed , abnormal
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 ZFA:0000368 integument integument colorless , abnormal
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 ZFA:0001069 ventral fin fold ventral fin fold absent , abnormal
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 ZFA:0001094 whole organism whole organism dead , abnormal
whole organism decreased size , abnormal
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 ZFA:0001120 neuroectoderm neuroectoderm wholly dorsalized , abnormal
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 ZFA:0001367 forebrain midbrain boundary forebrain midbrain boundary amorphous , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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