ENSDARG00000009470


Danio rerio

Features
Gene ID: ENSDARG00000009470
  
Biological name :hnf1a
  
Synonyms : hnf1a / HNF1 homeobox a
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 8
Strand: 1
Band:
Gene start: 39802506
Gene end: 39817167
  
Corresponding Affymetrix probe sets: Dr.15427.1.S2_at (Zebrafish Array)   NM_170764_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000006784
Ensembl peptide - ENSDARP00000068655
NCBI entrez gene - 266961     See in Manteia.
RefSeq - NM_170764
RefSeq Peptide - NP_739570
swissprot - F2Z4S1
swissprot - Q4L1M9
ZFIN ID - ZDB-GENE-021206-12
Ensembl - ENSDARG00000009470
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
hnf1ba / HNF1 homeobox Ba / HNF1B* / P35680* / P27889* / HNF1 homeobox B* / Hepatocyte nuclear factor 1-beta *ENSDARG0000000661542
Q8UW00 / hnf1bb / HNF1 homeobox Bb / HNF1B* / P27889* / P35680* / HNF1 homeobox B* / Hepatocyte nuclear factor 1-beta *ENSDARG0000002229539
zgc:91944ENSDARG0000003588714
CABZ01078261.1 / HMBOX1* / Q6NT76* / homeobox containing 1*ENSDARG0000010928714
hmbox1a / homeobox containing 1a / HMBOX1* / Q6NT76* / Q8BJA3* / homeobox containing 1* / Mus musculus homeobox containing 1 (Hmbox1), transcript variant 3, mRNA.*ENSDARG0000002708213


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR006897  Hepatocyte nuclear factor 1, beta isoform, C-terminal
 IPR006898  Hepatocyte nuclear factor 1, alpha isoform C-terminal
 IPR006899  Hepatocyte nuclear factor 1, N-terminal
 IPR009057  Homeobox-like domain superfamily
 IPR010982  Lambda repressor-like, DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003323 type B pancreatic cell development IMP
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0031018 endocrine pancreas development IMP
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 cellular_componentGO:0005634 nucleus IC
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0003677 DNA binding ISS
 molecular_functionGO:0003700 DNA-binding transcription factor activity ISS
 molecular_functionGO:0046983 protein dimerization activity ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0009102 pancreatic B cell pancreatic B cell increased amount , abnormal
pancreatic B cell decreased amount , abnormal
pancreatic B cell decreased area , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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