ENSDARG00000009511
Danio rerio response tnfa necrosis signaling tnfr tumour factor domain liver bacterium regulation receptor activity regeneration fin intestinal epithelial membrane -induced pathway cell alpha lymphotoxin-alpha factor-like superfamily development molecule bacterial origin autophagy inflammatory
Features Gene ID: ENSDARG00000009511 Biological name :tnfa Synonyms : tnfa / tumor necrosis factor a (TNF superfamily, member 2) Possible biological names infered from orthology : LTA / lymphotoxin A / lymphotoxin alpha / P01374 / P01375 / P06804 / P09225 / TNF / tumor necrosis factor Species: Danio rerio Chr. number: 19 Strand: 1 Band: Gene start: 27019432 Gene end: 27024019 Corresponding Affymetrix probe sets: Cross references: Ensembl peptide - ENSDARP00000025726 NCBI entrez gene - 405785
See in Manteia .
RefSeq - NM_212859 RefSeq Peptide - NP_998024 swissprot - Q1L8A5 ZFIN ID - ZDB-GENE-050317-1 Ensembl - ENSDARG00000009511
See expression report in BioGPS See gene description in Wikigenes See co-cited genes in PubMed Ortholog prediction (from Ensembl )
Paralog prediction (from Ensembl ) tnfb / tumor necrosis factor b (TNF superfamily, member 2) / LTA* / TNF* / P01375* / P06804* / P09225* / P01374* / lymphotoxin A* / lymphotoxin alpha* / tumor necrosis factor* ENSDARG00000013598 38 faslg / Fas ligand (TNF superfamily, member 6) / P48023* / Fas ligand* ENSDARG00000098913 16
Protein motifs (from Interpro )
Gene Ontology (GO ) anatomical structure development response to external stimulus response to chemical response to biotic stimulus catabolic process cellular metabolic process process utilizing autophagic mechanism response to stress immune response cell communication regulation of molecular function cellular response to stimulus developmental growth regulation of biological quality system process digestion anatomical structure development response to external stimulus response to chemical response to biotic stimulus catabolic process cellular metabolic process process utilizing autophagic mechanism response to stress immune response cell communication regulation of molecular function cellular response to stimulus developmental growth regulation of biological quality system process digestion anatomical structure development response to external stimulus response to chemical response to biotic stimulus catabolic process cellular metabolic process process utilizing autophagic mechanism response to stress immune response cell communication regulation of molecular function cellular response to stimulus developmental growth regulation of biological quality system process digestion anatomical structure development response to external stimulus response to chemical response to biotic stimulus catabolic process cellular metabolic process process utilizing autophagic mechanism response to stress immune response cell communication regulation of molecular function cellular response to stimulus developmental growth regulation of biological quality system process digestion anatomical structure development response to external stimulus response to chemical response to biotic stimulus catabolic process cellular metabolic process process utilizing autophagic mechanism response to stress immune response cell communication regulation of molecular function cellular response to stimulus developmental growth regulation of biological quality system process digestion anatomical structure development response to external stimulus response to chemical response to biotic stimulus catabolic process cellular metabolic process process utilizing autophagic mechanism response to stress immune response cell communication regulation of molecular function cellular response to stimulus developmental growth regulation of biological quality system process digestion anatomical structure development response to external stimulus response to chemical response to biotic stimulus catabolic process cellular metabolic process process utilizing autophagic mechanism response to stress immune response cell communication regulation of molecular function cellular response to stimulus developmental growth regulation of biological quality system process digestion anatomical structure development response to external stimulus response to chemical response to biotic stimulus catabolic process cellular metabolic process process utilizing autophagic mechanism response to stress immune response cell communication regulation of molecular function cellular response to stimulus developmental growth regulation of biological quality system process digestion anatomical structure development response to external stimulus response to chemical response to biotic stimulus catabolic process cellular metabolic process process utilizing autophagic mechanism response to stress immune response cell communication regulation of molecular function cellular response to stimulus developmental growth regulation of biological quality system process digestion anatomical structure development response to external stimulus response to chemical response to biotic stimulus catabolic process cellular metabolic process process utilizing autophagic mechanism response to stress immune response cell communication regulation of molecular function cellular response to stimulus developmental growth regulation of biological quality system process digestion anatomicanatomical structure development responseresponse to external stimulus responseresponse to chemical responseresponse to biotic stimulus catabolicatabolic process cellularcellular metabolic process process process utilizing autophagic mechanism responseresponse to stress immune rimmune response cell comcell communication regulatiregulation of molecular function cellularcellular response to stimulus developmdevelopmental growth regulatiregulation of biological quality system psystem process digestiodigestion protein binding receptor regulator activity protein binding receptor regulator activity protein binding receptor regulator activity protein binding receptor regulator activity protein binding receptor regulator activity protein binding receptor regulator activity protein binding receptor regulator activity protein binding receptor regulator activity protein binding receptor regulator activity protein binding receptor regulator activity protein bindingprotein binding receptor regulator activityreceptor regulator activity extracellular region membrane extracellular region membrane extracellular region membrane extracellular region membrane extracellular region membrane extracellular region membrane extracellular region membrane extracellular region membrane extracellular region membrane extracellular region membrane extracellular regionextracellular region membranemembrane
Pathways (from Reactome )
Phenotype (from MGI , Zfin or HPO ) ZFA:0000119 retinal inner nuclear layer retinal inner nuclear layer cell proliferation delayed , abnormal retinal inner nuclear layer cell proliferation decreased process quality , abnormal
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ZFA:0000123 liver liver decreased size , abnormal
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ZFA:0001094 whole organism whole organism life span , ameliorated whole organism increased amount , abnormal
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ZFA:0001269 regenerating fin regenerating fin decreased length , abnormal
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ZFA:0009111 hepatocyte hepatocyte decreased distribution , abnormal hepatocyte decreased amount , abnormal
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ZFA:0009127 photoreceptor cell photoreceptor cell regeneration process quality , abnormal
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ZFA:0009399 intestinal epithelial cell intestinal epithelial cell decreased height , abnormal
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Interacting proteins (from Reactome )No match
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