ENSDARG00000009738


Danio rerio

Features
Gene ID: ENSDARG00000009738
  
Biological name :cacnb4a
  
Synonyms : cacnb4a / calcium channel, voltage-dependent, beta 4a subunit
  
Possible biological names infered from orthology : AC068547.1 / CACNB4 / calcium voltage-gated channel auxiliary subunit beta 4 / Mus musculus calcium channel, voltage-dependent, beta 4 subunit (Cacnb4), transcript variant 6, mRNA. / O00305 / Q8R0S4
  
Species: Danio rerio
  
Chr. number: 9
Strand: 1
Band:
Gene start: 38074082
Gene end: 38130085
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000022331
Ensembl peptide - ENSDARP00000119670
Ensembl peptide - ENSDARP00000107502
NCBI entrez gene - 562422     See in Manteia.
RefSeq - NM_001113519
RefSeq Peptide - NP_001106991
swissprot - B0F0D0
swissprot - A8WHZ5
swissprot - A8WHZ4
ZFIN ID - ZDB-GENE-080320-2
Ensembl - ENSDARG00000009738
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 AC068547.1ENSG00000283228Homo sapiens
 CACNB4ENSG00000182389Homo sapiens
 Cacnb4ENSMUSG00000017412Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cacnb4b / calcium channel, voltage-dependent, beta 4b subunit / O00305* / CACNB4* / Q8R0S4* / AC068547.1* / calcium voltage-gated channel auxiliary subunit beta 4* / Mus musculus calcium ch...ENSDARG0000006217483
cacnb3a / calcium channel, voltage-dependent, beta 3a / P54285* / P54284* / CACNB3* / calcium voltage-gated channel auxiliary subunit beta 3* / Mus musculus calcium channel, voltage-depende...ENSDARG0000000188161
cacnb1 / calcium channel, voltage-dependent, beta 1 subunit / Q02641* / Q8R3Z5* / calcium voltage-gated channel auxiliary subunit beta 1* / Voltage-dependent L-type calcium channel subunit beta-1 *ENSDARG0000000216759
cacnb2a / calcium channel, voltage-dependent, beta 2a / CACNB2* / Q08289* / Q8CC27* / calcium voltage-gated channel auxiliary subunit beta 2* / Voltage-dependent L-type calcium channel subu...ENSDARG0000009904556
cacnb3b / calcium channel, voltage-dependent, beta 3b / P54285* / P54284* / CACNB3* / calcium voltage-gated channel auxiliary subunit beta 3* / Mus musculus calcium channel, voltage-depende...ENSDARG0000007603055
cacnb2b / calcium channel, voltage-dependent, beta 2b / CACNB2* / Q08289* / Q8CC27* / calcium voltage-gated channel auxiliary subunit beta 2* / Voltage-dependent L-type calcium channel subu...ENSDARG0000005556546


Protein motifs (from Interpro)
Interpro ID Name
 IPR000584  Voltage-dependent calcium channel, L-type, beta subunit
 IPR001452  SH3 domain
 IPR008079  Voltage-dependent calcium channel, L-type, beta-3 subunit
 IPR008145  Guanylate kinase/L-type calcium channel beta subunit
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007268 chemical synaptic transmission IBA
 biological_processGO:0007528 neuromuscular junction development IBA
 biological_processGO:0055113 epiboly involved in gastrulation with mouth forming second IMP
 biological_processGO:0070588 calcium ion transmembrane transport IEA
 biological_processGO:1901385 regulation of voltage-gated calcium channel activity IBA
 cellular_componentGO:0005891 voltage-gated calcium channel complex IBA
 molecular_functionGO:0005245 voltage-gated calcium channel activity IEA
 molecular_functionGO:0008331 high voltage-gated calcium channel activity IBA


Pathways (from Reactome)
Pathway description
Presynaptic depolarization and calcium channel opening
Phase 0 - rapid depolarisation
Phase 2 - plateau phase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
Show

 ZFA:0000088 YSL YSL nucleus dispersed , abnormal
YSL nucleus increased size , abnormal
YSL nucleus decreased size , abnormal
YSL nucleus mislocalised , abnormal
YSL nucleus aggregated , abnormal
Show

 ZFA:0000541 marginal blastomere marginal blastomere necrotic , abnormal
Show

 ZFA:0001094 whole organism whole organism dead , abnormal
whole organism malformed , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr