ENSDARG00000062174


Danio rerio

Features
Gene ID: ENSDARG00000062174
  
Biological name :cacnb4b
  
Synonyms : cacnb4b / calcium channel, voltage-dependent, beta 4b subunit
  
Possible biological names infered from orthology : AC068547.1 / CACNB4 / calcium voltage-gated channel auxiliary subunit beta 4 / Mus musculus calcium channel, voltage-dependent, beta 4 subunit (Cacnb4), transcript variant 6, mRNA. / O00305 / Q8R0S4
  
Species: Danio rerio
  
Chr. number: 6
Strand: -1
Band:
Gene start: 14086688
Gene end: 14146979
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000083997
Ensembl peptide - ENSDARP00000124985
Ensembl peptide - ENSDARP00000109646
Ensembl peptide - ENSDARP00000084010
NCBI entrez gene - 678560     See in Manteia.
RefSeq - NM_001040318
RefSeq - NM_001113516
RefSeq Peptide - NP_001035408
RefSeq Peptide - NP_001106988
swissprot - B0F0D1
swissprot - B0F0C8
swissprot - B0F0C7
swissprot - B0F0C6
ZFIN ID - ZDB-GENE-060421-7907
Ensembl - ENSDARG00000062174
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 AC068547.1ENSG00000283228Homo sapiens
 CACNB4ENSG00000182389Homo sapiens
 Cacnb4ENSMUSG00000017412Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cacnb4a / calcium channel, voltage-dependent, beta 4a subunit / O00305* / CACNB4* / Q8R0S4* / AC068547.1* / calcium voltage-gated channel auxiliary subunit beta 4* / Mus musculus calcium ch...ENSDARG0000000973882
cacnb3a / calcium channel, voltage-dependent, beta 3a / P54285* / P54284* / CACNB3* / calcium voltage-gated channel auxiliary subunit beta 3* / Mus musculus calcium channel, voltage-depende...ENSDARG0000000188159
cacnb1 / calcium channel, voltage-dependent, beta 1 subunit / Q02641* / Q8R3Z5* / calcium voltage-gated channel auxiliary subunit beta 1* / Voltage-dependent L-type calcium channel subunit beta-1 *ENSDARG0000000216759
cacnb2a / calcium channel, voltage-dependent, beta 2a / CACNB2* / Q08289* / Q8CC27* / calcium voltage-gated channel auxiliary subunit beta 2* / Voltage-dependent L-type calcium channel subu...ENSDARG0000009904556
cacnb3b / calcium channel, voltage-dependent, beta 3b / P54285* / P54284* / CACNB3* / calcium voltage-gated channel auxiliary subunit beta 3* / Mus musculus calcium channel, voltage-depende...ENSDARG0000007603054
cacnb2b / calcium channel, voltage-dependent, beta 2b / CACNB2* / Q08289* / Q8CC27* / calcium voltage-gated channel auxiliary subunit beta 2* / Voltage-dependent L-type calcium channel subu...ENSDARG0000005556546


Protein motifs (from Interpro)
Interpro ID Name
 IPR000584  Voltage-dependent calcium channel, L-type, beta subunit
 IPR001452  SH3 domain
 IPR008145  Guanylate kinase/L-type calcium channel beta subunit
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007268 chemical synaptic transmission IBA
 biological_processGO:0007528 neuromuscular junction development IBA
 biological_processGO:0055113 epiboly involved in gastrulation with mouth forming second IMP
 biological_processGO:0070588 calcium ion transmembrane transport IEA
 biological_processGO:1901385 regulation of voltage-gated calcium channel activity IBA
 cellular_componentGO:0005891 voltage-gated calcium channel complex IEA
 molecular_functionGO:0005245 voltage-gated calcium channel activity IDA
 molecular_functionGO:0008331 high voltage-gated calcium channel activity IBA


Pathways (from Reactome)
Pathway description
Presynaptic depolarization and calcium channel opening
Phase 0 - rapid depolarisation
Phase 2 - plateau phase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
Show

 ZFA:0000088 YSL YSL nucleus dispersed , abnormal
YSL nucleus increased size , abnormal
YSL nucleus decreased size , abnormal
YSL nucleus mislocalised , abnormal
YSL nucleus aggregated , abnormal
Show

 ZFA:0000541 marginal blastomere marginal blastomere necrotic , abnormal
Show

 ZFA:0001094 whole organism whole organism dead , abnormal
whole organism malformed , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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