ENSDARG00000010267


Danio rerio

Features
Gene ID: ENSDARG00000010267
  
Biological name :dpydb
  
Synonyms : dihydropyrimidine dehydrogenase b / dpydb
  
Possible biological names infered from orthology : dihydropyrimidine dehydrogenase / Dihydropyrimidine dehydrogenase [NADP(+)] / DPYD / Q12882 / Q8CHR6
  
Species: Danio rerio
  
Chr. number: 2
Strand: -1
Band:
Gene start: 19824190
Gene end: 20120904
  
Corresponding Affymetrix probe sets: Dr.7007.1.A1_s_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000090906
Ensembl peptide - ENSDARP00000108791
Ensembl peptide - ENSDARP00000157388
swissprot - F1QUE6
swissprot - F1QX36
ZFIN ID - ZDB-GENE-040426-2459
Ensembl - ENSDARG00000010267
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DPYDENSGALG00000005509Gallus gallus
 DPYDENSG00000188641Homo sapiens
 DpydENSMUSG00000033308Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
dpyda.3 / dihydropyrimidine dehydrogenase a, tandem duplicate 3 / DPYD* / Q12882* / dihydropyrimidine dehydrogenase*ENSDARG0000008685355
dpyda.1 / dihydropyrimidine dehydrogenase a, tandem duplicate 1 / DPYD* / Q8CHR6* / Q12882* / dihydropyrimidine dehydrogenase* / Dihydropyrimidine dehydrogenase [NADP(+)] *ENSDARG0000010267119


Protein motifs (from Interpro)
Interpro ID Name
 IPR005720  Dihydroorotate dehydrogenase domain
 IPR009051  Alpha-helical ferredoxin
 IPR013785  Aldolase-type TIM barrel
 IPR017896  4Fe-4S ferredoxin-type, iron-sulphur binding domain
 IPR017900  4Fe-4S ferredoxin, iron-sulphur binding, conserved site
 IPR023753  FAD/NAD(P)-binding domain
 IPR028261  Dihydroprymidine dehydrogenase domain II


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0019483 beta-alanine biosynthetic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016627 oxidoreductase activity, acting on the CH-CH group of donors IEA
 molecular_functionGO:0017113 dihydropyrimidine dehydrogenase (NADP+) activity IEA
 molecular_functionGO:0051536 iron-sulfur cluster binding IEA
 molecular_functionGO:0051539 4 iron, 4 sulfur cluster binding IEA


Pathways (from Reactome)
Pathway description
Pyrimidine catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000010267 dpydb / dihydropyrimidine dehydrogenase b / DPYD* / Q8CHR6* / Q12882* / dihydropyrimidine dehydrogenase* / Dihydropyrimidine dehydrogenase [NADP(+)] *  / complex
 ENSDARG00000086853 dpyda.3 / dihydropyrimidine dehydrogenase a, tandem duplicate 3 / DPYD* / Q12882* / dihydropyrimidine dehydrogenase*  / complex






 

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