ENSDARG00000086853


Danio rerio

Features
Gene ID: ENSDARG00000086853
  
Biological name :dpyda.3
  
Synonyms : dihydropyrimidine dehydrogenase a, tandem duplicate 3 / dpyda.3
  
Possible biological names infered from orthology : dihydropyrimidine dehydrogenase / Dihydropyrimidine dehydrogenase [NADP(+)] / DPYD / Q12882 / Q8CHR6
  
Species: Danio rerio
  
Chr. number: 24
Strand: 1
Band:
Gene start: 30521619
Gene end: 30774116
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000141769
swissprot - A0A0R4IXT5
ZFIN ID - ZDB-GENE-131121-37
Ensembl - ENSDARG00000086853
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DPYDENSGALG00000005509Gallus gallus
 DPYDENSG00000188641Homo sapiens
 DpydENSMUSG00000033308Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
dpydb / dihydropyrimidine dehydrogenase b / DPYD* / Q8CHR6* / Q12882* / dihydropyrimidine dehydrogenase* / Dihydropyrimidine dehydrogenase [NADP(+)] *ENSDARG0000001026780
dpyda.1 / dihydropyrimidine dehydrogenase a, tandem duplicate 1 / DPYD* / Q8CHR6* / Q12882* / dihydropyrimidine dehydrogenase* / Dihydropyrimidine dehydrogenase [NADP(+)] *ENSDARG000001026710


Protein motifs (from Interpro)
Interpro ID Name
 IPR001295  Dihydroorotate dehydrogenase, conserved site
 IPR005720  Dihydroorotate dehydrogenase domain
 IPR013785  Aldolase-type TIM barrel
 IPR017896  4Fe-4S ferredoxin-type, iron-sulphur binding domain
 IPR017900  4Fe-4S ferredoxin, iron-sulphur binding, conserved site
 IPR023753  FAD/NAD(P)-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006207 "de novo" pyrimidine nucleobase biosynthetic process IEA
 biological_processGO:0019483 beta-alanine biosynthetic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004152 dihydroorotate dehydrogenase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016627 oxidoreductase activity, acting on the CH-CH group of donors IEA
 molecular_functionGO:0017113 dihydropyrimidine dehydrogenase (NADP+) activity IEA
 molecular_functionGO:0051539 4 iron, 4 sulfur cluster binding IEA


Pathways (from Reactome)
Pathway description
Pyrimidine catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000010267 dpydb / dihydropyrimidine dehydrogenase b / DPYD* / Q8CHR6* / Q12882* / dihydropyrimidine dehydrogenase* / Dihydropyrimidine dehydrogenase [NADP(+)] *  / complex
 ENSDARG00000086853 dpyda.3 / dihydropyrimidine dehydrogenase a, tandem duplicate 3 / DPYD* / Q12882* / dihydropyrimidine dehydrogenase*  / complex






 

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