ENSDARG00000010933


Danio rerio

Features
Gene ID: ENSDARG00000010933
  
Biological name :cacna1fa
  
Synonyms : cacna1fa / calcium channel, voltage-dependent, L type, alpha 1F subunit a
  
Possible biological names infered from orthology : CACNA1F / calcium voltage-gated channel subunit alpha1 F / O60840
  
Species: Danio rerio
  
Chr. number: 8
Strand: -1
Band:
Gene start: 44850710
Gene end: 44868020
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000123455
Ensembl peptide - ENSDARP00000147256
swissprot - F1QGT9
ZFIN ID - ZDB-GENE-091204-7
Ensembl - ENSDARG00000010933
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 O60840ENSG00000102001Homo sapiens
 Cacna1fENSMUSG00000031142Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cacna1fb / calcium channel, voltage-dependent, L type, alpha 1F subunit / O60840* / CACNA1F* / calcium voltage-gated channel subunit alpha1 F*ENSDARG0000002368377
cacna1da / calcium channel, voltage-dependent, L type, alpha 1D subunit, a / Q01668* / CACNA1D* / calcium voltage-gated channel subunit alpha1 D*ENSDARG0000010277368
cacna1c / calcium channel, voltage-dependent, L type, alpha 1C subunit / Q01815* / Q13936* / calcium voltage-gated channel subunit alpha1 C* / Voltage-dependent L-type calcium channel subun...ENSDARG0000000839865
cacna1sa / calcium channel, voltage-dependent, L type, alpha 1S subunit, a / Q13698* / CACNA1S* / calcium voltage-gated channel subunit alpha1 S*ENSDARG0000002945756
cacna1sb / calcium channel, voltage-dependent, L type, alpha 1S subunit, b / Q13698* / CACNA1S* / calcium voltage-gated channel subunit alpha1 S*ENSDARG0000004255255
cacna1ab / calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, b / O00555* / P97445* / CACNA1A* / calcium voltage-gated channel subunit alpha1 A* / Voltage-dependent P/Q-type ca...ENSDARG0000000692345
cacna1ba / calcium channel, voltage-dependent, N type, alpha 1B subunit, a / O55017* / Q00975* / CACNA1B* / calcium voltage-gated channel subunit alpha1 B* / Voltage-dependent N-type calciu...ENSDARG0000002173545
cacna1aa / calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, a / O00555* / CACNA1A* / calcium voltage-gated channel subunit alpha1 A*ENSDARG0000003790545
cacna1bb / calcium channel, voltage-dependent, N type, alpha 1B subunit, b / O55017* / Q00975* / CACNA1B* / calcium voltage-gated channel subunit alpha1 B* / Voltage-dependent N-type calciu...ENSDARG0000007929544
cacna1eb / calcium channel, voltage-dependent, R type, alpha 1E subunit b / Q15878* / CACNA1E* / calcium voltage-gated channel subunit alpha1 E*ENSDARG0000009561443
cacna1db / calcium channel, voltage-dependent, L type, alpha 1D subunit, b / Q01668* / CACNA1D* / calcium voltage-gated channel subunit alpha1 D*ENSDARG0000011064242
nalcn / sodium leak channel, non-selective / Q8IZF0*ENSDARG0000000183520
cacna1ea / calcium channel, voltage-dependent, R type, alpha 1E subunit a / Q15878* / CACNA1E* / calcium voltage-gated channel subunit alpha1 E*ENSDARG0000006234618
FO082780.1 / O60840* / CACNA1F* / calcium voltage-gated channel subunit alpha1 F*ENSDARG000001155280
cacna1db / calcium channel, voltage-dependent, L type, alpha 1D subunit, b / Q01668* / CACNA1D* / calcium voltage-gated channel subunit alpha1 D*ENSDARG000001156030


Protein motifs (from Interpro)
Interpro ID Name
 IPR002077  Voltage-dependent calcium channel, alpha-1 subunit
 IPR005446  Voltage-dependent calcium channel, L-type, alpha-1 subunit
 IPR005821  Ion transport domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0050808 synapse organization IMP
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0070588 calcium ion transmembrane transport IEA
 cellular_componentGO:0005891 voltage-gated calcium channel complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005245 voltage-gated calcium channel activity IEA
 molecular_functionGO:0005262 calcium channel activity IEA


Pathways (from Reactome)
Pathway description
Phase 0 - rapid depolarisation
Phase 2 - plateau phase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000107 eye eye quality , abnormal
Show

 ZFA:0001330 retinal outer plexiform layer retinal outer plexiform layer decreased thickness , abnormal
Show

 ZFA:0009262 retinal cone cell retinal cone cell quality , abnormal
retinal cone cell chemical synaptic transmission process quality , abnormal
retinal cone cell cone cell pedicle morphology , abnormal
retinal cone cell cone cell pedicle lacks parts or has fewer parts of type retinal cone cell ribbon synapse, abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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