ENSDARG00000042552


Danio rerio

Features
Gene ID: ENSDARG00000042552
  
Biological name :cacna1sb
  
Synonyms : cacna1sb / calcium channel, voltage-dependent, L type, alpha 1S subunit, b
  
Possible biological names infered from orthology : CACNA1S / calcium voltage-gated channel subunit alpha1 S / Q13698
  
Species: Danio rerio
  
Chr. number: 8
Strand: 1
Band:
Gene start: 25767610
Gene end: 25808403
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000062405
NCBI entrez gene - 405791     See in Manteia.
RefSeq - NM_214726
RefSeq Peptide - NP_999891
swissprot - Q6RKB0
ZFIN ID - ZDB-GENE-051227-1
Ensembl - ENSDARG00000042552
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CACNA1SENSGALG00000037744Gallus gallus
 Q13698ENSG00000081248Homo sapiens
 Cacna1sENSMUSG00000026407Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cacna1sa / calcium channel, voltage-dependent, L type, alpha 1S subunit, a / Q13698* / CACNA1S* / calcium voltage-gated channel subunit alpha1 S*ENSDARG0000002945773
cacna1c / calcium channel, voltage-dependent, L type, alpha 1C subunit / Q01815* / Q13936* / calcium voltage-gated channel subunit alpha1 C* / Voltage-dependent L-type calcium channel subun...ENSDARG0000000839859
cacna1da / calcium channel, voltage-dependent, L type, alpha 1D subunit, a / Q01668* / CACNA1D* / calcium voltage-gated channel subunit alpha1 D*ENSDARG0000010277356
cacna1fb / calcium channel, voltage-dependent, L type, alpha 1F subunit / O60840* / CACNA1F* / calcium voltage-gated channel subunit alpha1 F*ENSDARG0000002368352
cacna1ab / calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, b / O00555* / P97445* / CACNA1A* / calcium voltage-gated channel subunit alpha1 A* / Voltage-dependent P/Q-type ca...ENSDARG0000000692339
cacna1ba / calcium channel, voltage-dependent, N type, alpha 1B subunit, a / O55017* / Q00975* / CACNA1B* / calcium voltage-gated channel subunit alpha1 B* / Voltage-dependent N-type calciu...ENSDARG0000002173539
cacna1bb / calcium channel, voltage-dependent, N type, alpha 1B subunit, b / O55017* / Q00975* / CACNA1B* / calcium voltage-gated channel subunit alpha1 B* / Voltage-dependent N-type calciu...ENSDARG0000007929539
cacna1aa / calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, a / O00555* / CACNA1A* / calcium voltage-gated channel subunit alpha1 A*ENSDARG0000003790538
cacna1eb / calcium channel, voltage-dependent, R type, alpha 1E subunit b / Q15878* / CACNA1E* / calcium voltage-gated channel subunit alpha1 E*ENSDARG0000009561437
cacna1ea / calcium channel, voltage-dependent, R type, alpha 1E subunit a / Q15878* / CACNA1E* / calcium voltage-gated channel subunit alpha1 E*ENSDARG0000006234627
nalcn / sodium leak channel, non-selective / Q8IZF0*ENSDARG0000000183519
cacna1fa / calcium channel, voltage-dependent, L type, alpha 1F subunit a / O60840* / CACNA1F* / calcium voltage-gated channel subunit alpha1 F*ENSDARG0000001093319
cacna1db / calcium channel, voltage-dependent, L type, alpha 1D subunit, b / Q01668* / CACNA1D* / calcium voltage-gated channel subunit alpha1 D*ENSDARG0000011064214
FO082780.1 / O60840* / CACNA1F* / calcium voltage-gated channel subunit alpha1 F*ENSDARG0000011552811
cacna1db / calcium channel, voltage-dependent, L type, alpha 1D subunit, b / Q01668* / CACNA1D* / calcium voltage-gated channel subunit alpha1 D*ENSDARG000001156039


Protein motifs (from Interpro)
Interpro ID Name
 IPR002077  Voltage-dependent calcium channel, alpha-1 subunit
 IPR005446  Voltage-dependent calcium channel, L-type, alpha-1 subunit
 IPR005450  Voltage-dependent calcium channel, L-type, alpha-1S subunit
 IPR005821  Ion transport domain
 IPR014873  Voltage-dependent calcium channel, alpha-1 subunit, IQ domain
 IPR031649  Voltage-dependent L-type calcium channel, IQ-associated domain
 IPR031688  Voltage-gated calcium channel subunit alpha, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0070588 calcium ion transmembrane transport IEA
 biological_processGO:0086010 membrane depolarization during action potential IBA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0005891 voltage-gated calcium channel complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005245 voltage-gated calcium channel activity IEA
 molecular_functionGO:0005262 calcium channel activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008331 high voltage-gated calcium channel activity IBA


Pathways (from Reactome)
Pathway description
Phase 0 - rapid depolarisation
Phase 2 - plateau phase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000002167 cacnb1 / calcium channel, voltage-dependent, beta 1 subunit / Q02641* / Q8R3Z5* / calcium voltage-gated channel auxiliary subunit beta 1* / Voltage-dependent L-type calcium channel subunit beta-1 *  / complex
 ENSDARG00000078169 cacna2d2b / calcium channel, voltage-dependent, alpha 2/delta subunit 2b / Q6PHS9* / Q9NY47* / CACNA2D2* / calcium voltage-gated channel auxiliary subunit alpha2delta 2* / Voltage-dependent...  / complex
 ENSDARG00000103390 cacna2d2a / calcium channel, voltage-dependent, alpha 2/delta subunit 2a / Q9NY47* / CACNA2D2* / calcium voltage-gated channel auxiliary subunit alpha2delta 2*  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr