ENSDARG00000012340


Danio rerio

Features
Gene ID: ENSDARG00000012340
  
Biological name :ptpn11b
  
Synonyms : protein tyrosine phosphatase, non-receptor type 11, b / ptpn11b
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 23
Strand: 1
Band:
Gene start: 23918421
Gene end: 23995856
  
Corresponding Affymetrix probe sets: Dr.13952.1.A1_at (Zebrafish Array)   NM_200454_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000046950
NCBI entrez gene - 393426     See in Manteia.
RefSeq - NM_200454
RefSeq - XM_005162157
RefSeq Peptide - NP_956748
swissprot - F1R1Z7
ZFIN ID - ZDB-GENE-040426-1158
Ensembl - ENSDARG00000012340
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000035017Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ptpn11a / protein tyrosine phosphatase, non-receptor type 11, a / PTPN11* / P35235* / Q06124* / Tyrosine-protein phosphatase non-receptor type 11 * / protein tyrosine phosphatase, non-recep...ENSDARG0000002033468
ptpn6 / protein tyrosine phosphatase, non-receptor type 6 / P29350* / P29351*ENSDARG0000008904356
ptprna / protein tyrosine phosphatase, receptor type, Na / PTPRN* / Q16849* / protein tyrosine phosphatase, receptor type N*ENSDARG0000005864622
ptprnb / protein tyrosine phosphatase, receptor type, Nb / PTPRN* / Q16849* / protein tyrosine phosphatase, receptor type N*ENSDARG0000007704721
ptprr / protein tyrosine phosphatase, receptor type, r / Q15256* / Q62132*ENSDARG0000010574421
ptprn2 / protein tyrosine phosphatase, receptor type, N polypeptide 2 / P80560* / Q92932* / protein tyrosine phosphatase, receptor type N2*ENSDARG0000003597020
ptpn5 / protein tyrosine phosphatase, non-receptor type 5 / P54829* / P54830* / Tyrosine-protein phosphatase non-receptor type 5 *ENSDARG0000007486619


Protein motifs (from Interpro)
Interpro ID Name
 IPR000242  PTP type protein phosphatase
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR000980  SH2 domain
 IPR003595  Protein-tyrosine phosphatase, catalytic
 IPR012152  Protein-tyrosine phosphatase, non-receptor type-6, -11
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR029021  Protein-tyrosine phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0048703 embryonic viscerocranium morphogenesis IGI
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000076 swim bladder swim bladder absent , abnormal
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 ZFA:0000107 eye eye edematous , abnormal
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 ZFA:0000114 heart heart edematous , abnormal
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 ZFA:0001094 whole organism whole organism decreased length , abnormal
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 ZFA:0001114 head head malformed , abnormal
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 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage shape , abnormal
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 ZFA:0001458 cranial cartilage cranial cartilage malformed , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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