ENSDARG00000014017


Danio rerio

Features
Gene ID: ENSDARG00000014017
  
Biological name :rrm1
  
Synonyms : ribonucleotide reductase M1 polypeptide / rrm1
  
Possible biological names infered from orthology : P07742 / P23921 / Ribonucleoside-diphosphate reductase large subunit / ribonucleotide reductase catalytic subunit M1
  
Species: Danio rerio
  
Chr. number: 21
Strand: -1
Band:
Gene start: 30772043
Gene end: 30787414
  
Corresponding Affymetrix probe sets: Dr.9746.1.S1_a_at (Zebrafish Array)   NM_131455_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000010800
NCBI entrez gene - 30740     See in Manteia.
RefSeq - NM_131455
RefSeq Peptide - NP_571530
swissprot - F1R2K9
ZFIN ID - ZDB-GENE-990415-247
Ensembl - ENSDARG00000014017
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RRM1ENSGALG00000017350Gallus gallus
 RRM1ENSG00000167325Homo sapiens
 Rrm1ENSMUSG00000030978Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000788  Ribonucleotide reductase large subunit, C-terminal
 IPR005144  ATP-cone domain
 IPR008926  Ribonucleotide reductase R1 subunit, N-terminal
 IPR013346  Ribonucleotide reductase, class I , alpha subunit
 IPR013509  Ribonucleotide reductase large subunit, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA


Pathways (from Reactome)
Pathway description
Interconversion of nucleotide di- and triphosphates


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0001094 whole organism whole organism shape , abnormal
whole organism sigmoid , abnormal
Show

 ZFA:0001114 head head shape , abnormal
head decreased width , abnormal
head pointed , abnormal
Show

 ZFA:0001115 trunk trunk sigmoid , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000014017 rrm1 / ribonucleotide reductase M1 polypeptide / P07742* / P23921* / ribonucleotide reductase catalytic subunit M1* / Ribonucleoside-diphosphate reductase large subunit *  / complex
 ENSDARG00000031435 zgc:56493 / TXN* / Txn1* / Q6A555* / Q86VQ3* / P10639* / Q69AB2* / TXNDC2* / TXNDC8* / P10599* / thioredoxin* / thioredoxin 1* / thioredoxin domain containing 2* / thioredoxin domain contai...  / reaction
 ENSDARG00000033367 rrm2b / ribonucleotide reductase M2 b / Q7LG56* / Q6PEE3* / ribonucleotide reductase regulatory TP53 inducible subunit M2B* / Mus musculus ribonucleotide reductase M2 B (TP53 inducible) (Rr...  / complex
 ENSDARG00000044125 txn / thioredoxin / Txn1* / Q6A555* / Q86VQ3* / TXNDC8* / P10599* / P10639* / Q69AB2* / TXNDC2* / thioredoxin 1* / thioredoxin domain containing 2* / thioredoxin domain containing 8* / thio...  / reaction
 ENSDARG00000020711 rrm2 / P79733 / ribonucleotide reductase M2 polypeptide / P31350* / P11157* / AC007240.1* / ribonucleotide reductase regulatory subunit M2* / Ribonucleoside-diphosphate reductase subunit M2 *  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr