ENSGALG00000017350


Gallus gallus

Features
Gene ID: ENSGALG00000017350
  
Biological name :RRM1
  
Synonyms : ribonucleoside-diphosphate reductase large subunit / RRM1
  
Possible biological names infered from orthology : P07742 / P23921 / ribonucleotide reductase catalytic subunit M1
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 194676693
Gene end: 194694707
  
Corresponding Affymetrix probe sets: Gga.4514.2.S1_s_at (Chicken Array)   Gga.4514.3.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000027981
Ensembl peptide - ENSGALP00000062501
NCBI entrez gene - 419081     See in Manteia.
RefSeq - NM_001030837
RefSeq Peptide - NP_001026008
swissprot - E1C4Q0
swissprot - A0A1L1RUK4
Ensembl - ENSGALG00000017350
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rrm1ENSDARG00000014017Danio rerio
 RRM1ENSG00000167325Homo sapiens
 Rrm1ENSMUSG00000030978Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000788  Ribonucleotide reductase large subunit, C-terminal
 IPR005144  ATP-cone domain
 IPR008926  Ribonucleotide reductase R1 subunit, N-terminal
 IPR013346  Ribonucleotide reductase, class I , alpha subunit
 IPR013509  Ribonucleotide reductase large subunit, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0009263 deoxyribonucleotide biosynthetic process IEA
 biological_processGO:0051259 protein complex oligomerization IEA
 biological_processGO:0051290 protein heterotetramerization IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005971 ribonucleoside-diphosphate reductase complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0017076 purine nucleotide binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0097718 disordered domain specific binding IEA


Pathways (from Reactome)
Pathway description
Interconversion of nucleotide di- and triphosphates


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000017350 RRM1 / ribonucleoside-diphosphate reductase large subunit / P07742* / P23921* / ribonucleotide reductase catalytic subunit M1*  / complex
 ENSGALG00000015704 TXN / P08629 / Thioredoxin / Txn1* / TXNDC2* / P10599* / P10639* / Q86VQ3* / thioredoxin 1* / thioredoxin domain containing 2* / thioredoxin domain containing 2 (spermatozoa)*  / reaction
 ENSGALG00000016442 RRM2* / P31350* / P11157* / AC007240.1* / ribonucleotide reductase regulatory subunit M2* / Ribonucleoside-diphosphate reductase subunit M2 *  / complex
 ENSGALG00000040921 RRM2B / ribonucleotide reductase regulatory TP53 inducible subunit M2B / Q6PEE3* / Q7LG56* / Mus musculus ribonucleotide reductase M2 B (TP53 inducible) (Rrm2b), transcript variant 3, mRNA.*  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr