ENSDARG00000017928


Danio rerio

Features
Gene ID: ENSDARG00000017928
  
Biological name :xrcc3
  
Synonyms : X-ray repair complementing defective repair in Chinese hamster cells 3 / xrcc3
  
Possible biological names infered from orthology : O43542 / Q9CXE6 / X-ray repair cross complementing 3
  
Species: Danio rerio
  
Chr. number: 20
Strand: -1
Band:
Gene start: 20896622
Gene end: 20901558
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000004619
Ensembl peptide - ENSDARP00000113695
swissprot - A5PM99
swissprot - Q5TZD9
ZFIN ID - ZDB-GENE-050320-116
Ensembl - ENSDARG00000017928
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 XRCC3ENSGALG00000011533Gallus gallus
 XRCC3ENSG00000126215Homo sapiens
 Xrcc3ENSMUSG00000021287Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
rad51c / RAD51 paralog C / O43502* / Q924H5* / DNA repair 3 *ENSDARG0000006891925
rad51b / RAD51 paralog B / O15315* / O35719* / DNA repair 2 *ENSDARG0000003704623
rad51d / RAD51 paralog D / O75771*ENSDARG0000002640019


Protein motifs (from Interpro)
Interpro ID Name
 IPR013632  DNA recombination and repair protein Rad51-like, C-terminal
 IPR016467  DNA recombination and repair protein, RecA-like
 IPR020588  DNA recombination and repair protein RecA-like, ATP-binding domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR033925  Rad51/DMC1/RadA


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000707 meiotic DNA recombinase assembly IBA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006312 mitotic recombination IBA
 biological_processGO:0007131 reciprocal meiotic recombination IBA
 biological_processGO:0010212 response to ionizing radiation IBA
 biological_processGO:0042148 strand invasion IBA
 cellular_componentGO:0005657 replication fork IBA
 cellular_componentGO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex IBA
 molecular_functionGO:0000150 recombinase activity IBA
 molecular_functionGO:0000400 four-way junction DNA binding IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003690 double-stranded DNA binding IBA
 molecular_functionGO:0003697 single-stranded DNA binding IBA
 molecular_functionGO:0004520 endodeoxyribonuclease activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008094 DNA-dependent ATPase activity IBA


Pathways (from Reactome)
Pathway description
HDR through Homologous Recombination (HRR)
Resolution of D-loop Structures through Holliday Junction Intermediates
Homologous DNA Pairing and Strand Exchange


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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