ENSDARG00000018750


Danio rerio

Features
Gene ID: ENSDARG00000018750
  
Biological name :npr1b
  
Synonyms : natriuretic peptide receptor 1b / npr1b
  
Possible biological names infered from orthology : natriuretic peptide receptor 1 / NPR1 / P16066 / P18293
  
Species: Danio rerio
  
Chr. number: 16
Strand: 1
Band:
Gene start: 28908478
Gene end: 28991376
  
Corresponding Affymetrix probe sets: Dr.16297.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000010052
Ensembl peptide - ENSDARP00000125043
swissprot - E7F3T9
swissprot - F8W5M5
ZFIN ID - ZDB-GENE-100805-4
Ensembl - ENSDARG00000018750
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000037869Gallus gallus
 NPR1ENSG00000169418Homo sapiens
 Npr1ENSMUSG00000027931Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
npr1a / natriuretic peptide receptor 1a / NPR1* / P16066* / P18293* / natriuretic peptide receptor 1*ENSDARG0000003175170
npr2 / natriuretic peptide receptor 2 / P20594*ENSDARG0000010439357
si:dkey-37g12.1ENSDARG0000006026437
gucy2g / guanylate cyclase 2g / Q6TL19*ENSDARG0000007677633
gc2 / guanylyl cyclase 2 / GUCY2F* / P51841* / Q5SDA5* / Retinal guanylyl cyclase 2 * / guanylate cyclase 2F, retinal*ENSDARG0000001832931
gucy2f / guanylate cyclase 2F, retinalENSDARG0000002550431
gucy2d / guanylate cyclase 2D, retinal / Gucy2e* / P52785* / Q02846* / Guanylyl cyclase GC-E *ENSDARG0000002682030
si:ch73-139e5.4 / GUCY2C* / P25092* / Q3UWA6* / guanylate cyclase 2C* / Heat-stable enterotoxin receptor *ENSDARG0000005604528
gucy2c / guanylate cyclase 2C / P25092*ENSDARG0000001432025
si:dkey-239n17.6ENSDARG0000009584816
gucy1b2 / guanylate cyclase 1, soluble, beta 2ENSDARG0000005659115
gucy1a1 / guanylate cyclase 1 soluble subunit alpha 1 / Q02108* / Q9ERL9* / guanylate cyclase 1, soluble, alpha 1*ENSDARG0000001378714
gucy1b1 / guanylate cyclase 1 soluble subunit beta 1 / O54865* / Q02153* / guanylate cyclase 1, soluble, beta 1*ENSDARG0000008679014
GUCY1A2 / guanylate cyclase 1 soluble subunit alpha 2 / P33402*ENSDARG0000009318513
si:ch211-215j19.12ENSDARG0000010407211


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001054  Adenylyl cyclase class-3/4/guanylyl cyclase
 IPR001170  Adenylyl cyclase class-4/guanylyl cyclase
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR001828  Receptor, ligand binding region
 IPR011009  Protein kinase-like domain superfamily
 IPR018297  Adenylyl cyclase class-4/guanylyl cyclase, conserved site
 IPR028082  Periplasmic binding protein-like I
 IPR029787  Nucleotide cyclase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006182 cGMP biosynthetic process IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007168 receptor guanylyl cyclase signaling pathway IBA
 biological_processGO:0009190 cyclic nucleotide biosynthetic process IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0008074 guanylate cyclase complex, soluble IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004383 guanylate cyclase activity IBA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0016849 phosphorus-oxygen lyase activity IEA
 molecular_functionGO:0016941 natriuretic peptide receptor activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr