ENSDARG00000014320


Danio rerio

Features
Gene ID: ENSDARG00000014320
  
Biological name :gucy2c
  
Synonyms : guanylate cyclase 2C / gucy2c
  
Possible biological names infered from orthology : Heat-stable enterotoxin receptor / P25092 / Q3UWA6
  
Species: Danio rerio
  
Chr. number: 3
Strand: -1
Band:
Gene start: 3765831
Gene end: 3798755
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000130088
swissprot - A0A0R4IA00
ZFIN ID - ZDB-GENE-091118-67
Ensembl - ENSDARG00000014320
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GUCY2CENSGALG00000011838Gallus gallus
 GUCY2CENSG00000070019Homo sapiens
 Gucy2cENSMUSG00000042638Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
si:ch73-139e5.4 / GUCY2C* / P25092* / Q3UWA6* / guanylate cyclase 2C* / Heat-stable enterotoxin receptor *ENSDARG0000005604562
gc2 / guanylyl cyclase 2 / GUCY2F* / P51841* / Q5SDA5* / Retinal guanylyl cyclase 2 * / guanylate cyclase 2F, retinal*ENSDARG0000001832929
gucy2f / guanylate cyclase 2F, retinalENSDARG0000002550429
gucy2d / guanylate cyclase 2D, retinal / Gucy2e* / P52785* / Q02846* / Guanylyl cyclase GC-E *ENSDARG0000002682028
npr1a / natriuretic peptide receptor 1a / NPR1* / P16066* / P18293* / natriuretic peptide receptor 1*ENSDARG0000003175127
npr1b / natriuretic peptide receptor 1b / NPR1* / P16066* / P18293* / natriuretic peptide receptor 1*ENSDARG0000001875026
gucy2g / guanylate cyclase 2g / Q6TL19*ENSDARG0000007677626
npr2 / natriuretic peptide receptor 2 / P20594*ENSDARG0000010439326
si:dkey-37g12.1ENSDARG0000006026425
gucy1b2 / guanylate cyclase 1, soluble, beta 2ENSDARG0000005659114
gucy1a1 / guanylate cyclase 1 soluble subunit alpha 1 / Q02108* / Q9ERL9* / guanylate cyclase 1, soluble, alpha 1*ENSDARG0000001378713
gucy1b1 / guanylate cyclase 1 soluble subunit beta 1 / O54865* / Q02153* / guanylate cyclase 1, soluble, beta 1*ENSDARG0000008679013
GUCY1A2 / guanylate cyclase 1 soluble subunit alpha 2 / P33402*ENSDARG0000009318513
si:ch211-215j19.12ENSDARG0000010407210
si:dkey-239n17.6ENSDARG000000958482


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001054  Adenylyl cyclase class-3/4/guanylyl cyclase
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR011009  Protein kinase-like domain superfamily
 IPR018297  Adenylyl cyclase class-4/guanylyl cyclase, conserved site
 IPR028082  Periplasmic binding protein-like I
 IPR029787  Nucleotide cyclase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006182 cGMP biosynthetic process IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0009190 cyclic nucleotide biosynthetic process IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004383 guanylate cyclase activity IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0016849 phosphorus-oxygen lyase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr