ENSDARG00000018944


Danio rerio

Features
Gene ID: ENSDARG00000018944
  
Biological name :hoga1
  
Synonyms : 4-hydroxy-2-oxoglutarate aldolase 1 / hoga1 / Q6NY77
  
Possible biological names infered from orthology : 4-hydroxy-2-oxoglutarate aldolase, mitochondrial / Q86XE5 / Q9DCU9
  
Species: Danio rerio
  
Chr. number: 22
Strand: 1
Band:
Gene start: 34710036
Gene end: 34732882
  
Corresponding Affymetrix probe sets: Dr.25699.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000021126
Ensembl peptide - ENSDARP00000129648
NCBI entrez gene - 405806     See in Manteia.
swissprot - Q6NY77
swissprot - X1WHD6
ZFIN ID - ZDB-GENE-040426-2242
Ensembl - ENSDARG00000018944
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HOGA1ENSGALG00000006134Gallus gallus
 HOGA1ENSG00000241935Homo sapiens
 Hoga1ENSMUSG00000025176Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
npl / N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) / Q9BXD5* / N-acetylneuraminate pyruvate lyase*ENSDARG0000000939023


Protein motifs (from Interpro)
Interpro ID Name
 IPR002220  DapA-like
 IPR013785  Aldolase-type TIM barrel
 IPR020625  Schiff base-forming aldolase, active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0009436 glyoxylate catabolic process ISS
 cellular_componentGO:0005739 mitochondrion IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0008700 4-hydroxy-2-oxoglutarate aldolase activity ISS
 molecular_functionGO:0016829 lyase activity IEA


Pathways (from Reactome)
Pathway description
Glyoxylate metabolism and glycine degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000018944 hoga1 / Q6NY77 / 4-hydroxy-2-oxoglutarate aldolase 1 / Q86XE5* / Q9DCU9* / 4-hydroxy-2-oxoglutarate aldolase, mitochondrial *  / complex






 

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