ENSDARG00000019747


Danio rerio

Features
Gene ID: ENSDARG00000019747
  
Biological name :hsd3b2
  
Synonyms : hsd3b2 / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
  
Possible biological names infered from orthology : Gm10681 / Gm4450 / HSD3B1 / Hsd3b3 / Hsd3b4 / Hsd3b5 / Hsd3b6 / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 4 / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5 / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6 / O35469 / P14060 / P24815 / P26149 / P26150 / P26439 / predicted gene 10681 / Q61694 / Q61767
  
Species: Danio rerio
  
Chr. number: 20
Strand: 1
Band:
Gene start: 1272526
Gene end: 1276175
  
Corresponding Affymetrix probe sets: Dr.24984.1.S1_at (Zebrafish Array)   NM_212797_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000025516
Ensembl peptide - ENSDARP00000114055
NCBI entrez gene - 373131     See in Manteia.
RefSeq - NM_212797
RefSeq Peptide - NP_997962
swissprot - Q5RIL7
swissprot - Q5RIL8
ZFIN ID - ZDB-GENE-030828-2
Ensembl - ENSDARG00000019747
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HSD3B1ENSGALG00000037951Gallus gallus
 HSD3B1ENSG00000203857Homo sapiens
 HSD3B2ENSG00000203859Homo sapiens
 Gm4450ENSMUSG00000090817Mus musculus
 Hsd3b1ENSMUSG00000027871Mus musculus
 Hsd3b2ENSMUSG00000063730Mus musculus
 Hsd3b3ENSMUSG00000062410Mus musculus
 Hsd3b4ENSMUSG00000095143Mus musculus
 Hsd3b5ENSMUSG00000038092Mus musculus
 Hsd3b6ENSMUSG00000027869Mus musculus
 Q61767ENSMUSG00000095388Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
hsd3b1 / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 / Hsd3b3* / Hsd3b4* / Hsd3b5* / Hsd3b6* / Q61767* / Gm4450* / HSD3B2* / O35469* / P14060* / P24815* / P...ENSDARG0000006992676
hsd3b7 / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase / Q9EQC1* / Q9H2F3* / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7*ENSDARG0000003696634
A8DZE7 / sdr42e1 / short chain dehydrogenase/reductase family 42E, member 1 / Q8WUS8* / Q9D665*ENSDARG0000009883829
sdr42e2 / short chain dehydrogenase/reductase family 42E, member 2 / A6NKP2*ENSDARG0000005991428
nsdhl / NAD(P) dependent steroid dehydrogenase-like / Q15738* / Q9R1J0* / Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating *ENSDARG0000009931525


Protein motifs (from Interpro)
Interpro ID Name
 IPR002225  3-beta hydroxysteroid dehydrogenase/isomerase
 IPR016040  NAD(P)-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006694 steroid biosynthetic process IMP
 biological_processGO:0048598 embryonic morphogenesis IMP
 biological_processGO:0055114 oxidation-reduction process IEA
 molecular_functionGO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity IDA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA


Pathways (from Reactome)
Pathway description
Androgen biosynthesis
Mineralocorticoid biosynthesis
Glucocorticoid biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001094 whole organism whole organism elongated , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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